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Tomoyuki Mutoh
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About

EDUCATION
2019 March Ph.D. in Medicine Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine
2012 March M.D. in Medicine Tohoku University Graduate School of Medicine

WORK EXPERIENCE
2020 April – Department of Rheumatology, Osaki Citizen Hospital
2018 July - 2019 February  Teaching Assistant  Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine
2017 July - 2018 February Teaching Assistant  Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine
2014 April - 2015 March Department of Internal Medicine, Center for Rheumatic Diseases, Dohgo Spa Hospital
2012 April - 2014 March Yamagata City Hospital Saiseikan

PUBLICATIONS
・Tomoyuki Mutoh, Katsuyoshi Iwabuchi, Yuuki Abe, et al. “A case of organizing pneumonia with rheumatoid arthritis and nontuberculous mycobacteriosis” Yamagata Saiseikan Med. J. 2014;39(1):62-69.
・Tomoyuki Mutoh, Chihiro Onami, and Takahiko Tsunoda. “Two probable cases of Izumi fever” Yamagata Saiseikan Med. J. 2014;39(1):79-83.
・Tomoyuki Mutoh, Yasuaki Okuda, Sho Mokuda, et al. “Study on the frequency and risk factors of moderate-to-severe sleep apnea syndrome in rheumatoid arthritis” Mod Rheumatol. 2016;26(5):681–684.
・Tsuyoshi Shirai, Tomoyuki Mutoh, Tomonori Ishii, et al. “THU0317 IDENTIFICATION OF ENDOTHELIAL PROTEIN C RECEPTOR AND SCAVENGER RECEPTOR CLASS B TYPE 1 AS MAJOR AUTOANTIGENS IN TAKAYASU ARTERITIS” Ann Rheum Dis. 2019;78 (Suppl 2).
・Tomoyuki Mutoh, Tsuyoshi Shirai, Hiroshi Fujii, et al. “Insufficient Use of Corticosteroids Results in Higher Relapse in Takayasu arteritis [abstract]” Arthritis Rheumatol. 2018;70 (Suppl 10).
・Tomoyuki Mutoh, Tomonori Ishii, Tsuyoshi Shirai, et al. “Refractory Takayasu arteritis successfully treated with rituximab: case-based review” Rheumatol Int. 2019;39(11): 1989-1994.
・Tsuyoshi Shirai, Tomoyuki Mutoh, Tomonori Ishii, et al. “THU0317 IDENTIFICATION OF ENDOTHELIAL PROTEIN C RECEPTOR AND SCAVENGER RECEPTOR CLASS B TYPE 1 AS MAJOR AUTOANTIGENS IN TAKAYASU ARTERITIS” Ann Rheum Dis. 2019;78 (Suppl 2).
・Tomoyuki Mutoh, Tsuyoshi Shirai, Tomonori Ishii, et al. “Endothelial Protein C Receptor and Scavenger Receptor Class B Type 1 Negatively Regulate Vascular Inflammation and Are Major Autoantigens in Takayasu Arteritis [abstract]” Arthritis Rheum. 2019;71 (Suppl 10).
・Tomoyuki Mutoh, Tsuyoshi Shirai, Hiroshi Fujii, et al. “Insufficient use of corticosteroids without immunosuppressants results in higher relapse in Takayasu arteritis” J Rheumatol. 2020;47(2):255-263.
・Tomoyuki Mutoh, Tsuyoshi Shirai, Tomonori Ishii, et al. “Identification of two major autoantigens negatively regulating endothelial activation in Takayasu arteritis” Nat Commun. 2020;11(1):1253.
・Tomoyuki Mutoh (corresponding author), Yuko Shirota, Azusa Ito, et al. “One after another retinal involvement in lupus” Eur J Rheumatol. 2021;8(2):111-112.
・Tomoyuki Mutoh (corresponding author), Tsuyoshi Shirai, Hiroko Sato, et al. “Multi-targeted therapy for refractory eosinophilic granulomatosis with polyangiitis characterized by intracerebral hemorrhage and cardiomyopathy: a case-based review” Rheumatol Int. 2022;42(11):2069-2076.
・Tomoyuki Mutoh (corresponding author), Taichi Nagai, Tsuyoshi Shirai, et al. “Predictive factors for retention of golimumab over a median 4-year duration in Japanese patients with rheumatoid arthritis in a real-world setting: A retrospective study and literature review” Int J Rheum Dis. 2022;25(3):335-343.
・Mikihiro Takahashi, Tomoyuki Mutoh (corresponding author), Susumu Ohtsu, Akira Tsukada. “Blistering Distal Dactylitis” Am J Med. 2022;135(11):E418-E419.
・Tomoyuki Mutoh (corresponding author), Keiichi Ohashi, Taichi Nagai, et al. “Upfront rituximab therapy for thrombotic thrombocytopenic purpura in systemic lupus erythematosus: a case-based review” Rheumatol Int. 2023;43(2):373-381.
・Tomoyuki Mutoh (corresponding author), Mikihiro Takahashi, Taichi Nagai, et al. “Does the BNT162b2 Vaccine Trigger Antimelanoma Differentiation-Associated Gene 5 Antibody-Positive Interstitial Lung Disease?” J Rheumatol. 2023;50(2):293-294.
・Tomoyuki Mutoh (corresponding author), Masataka Kudo, Akira Tsukada. ”Ixekizumab for brodalumab-induced articular involvement in psoriatic arthritis: beyond IL-17A inhibition” Rheumatol Int. 2023;43(8):1559-1561.
・Ryu Watanabe, Megumi Oshima, Norihiro Nishioka, Ken-Ei Sada, Kenji Nagasaka, Mitsuhiro Akiyama, Taiki Ando, Tomoaki Higuchi, Yoshino Inoue, Takashi Kida, Tomoyuki Mutoh, Akihiko Nakabayashi, Akira Onishi, Ryota Sakai, Daisuke Waki, Yosuke Yamada, Nobuyuki Yajima, Naoto Tamura, Shinya Kaname, and Masayoshi Harigai. “Systematic review and meta-analysis for 2023 clinical practice guidelines of the Japan research committee of the ministry of health, labour, and welfare for intractable vasculitis for the management of ANCA-associated vasculitis” Mod Rheumatol. 2023;33(5):982-989.
・Tomoyuki Mutoh (corresponding author), Sonoko Chikamatsu, Takatsuna Sasaki, et al. “Relapsing Polychondritis following PD-1 Blockade by an Immune Checkpoint Inhibitor” JMA J. 2023;6(4):552-555.
・Tomoyuki Mutoh (corresponding author), Tsuyoshi Shirai, Hiroshi Fujii. “Comment on: Association of anti-HSC70 autoantibodies with cutaneous ulceration and severe disease in juvenile dermatomyositis” Rheumatology (Oxford). 2023;62(11):e323-324.
・Tomoyuki Mutoh (corresponding author), Mamoru Narita, Taichi Nagai, et al. “Clinical Images: Multiple punched-out ulcerations on the abdomen in anti-melanoma differentiation-associated gene 5 dermatomyositis” Arthritis Rheumatol. 2024;76(1):150-1.
・Tomoyuki Mutoh (corresponding author), Soshi Okazaki, Tsuyoshi Shirai, Hiroko Sato, Susumu Ohtsu, Tomonori Ishii, Hiroshi Fujii. “Rheumatoid Factor Predicts Long-Term Retention Associated With Effectiveness of Certolizumab Pegol in Patients With Rheumatoid Arthritis: A Two-Center Retrospective Study” Int J Rheum Dis. 2025;28(3):e70173.
・Tomoyuki Mutoh (corresponding author), Hidetoshi Mitsui, Hiroshi Fujii. “Spontaneous Intramuscular Hemorrhage in Anti-melanoma Differentiation associated Gene 5 Antibody-positive Dermatomyositis” JMA J. 2025;8(2):641-645.
・Kentaro Mori, Tsuyoshi Shirai, Tomoyuki Mutoh, Jun Inoue, Fumiyoshi Fujishima, Satsuki Kubo, Hirofumi Watanabe, Satoko Sato, Mamoru Narita, Yosuke Hoshi, Hiroko Sato, Hiroshi Fujii. “Drug-induced liver injury related to avacopan therapy” Rheumatology (Oxford). 2025;64(5):2533-2540.
・Tomoyuki Mutoh (corresponding author), Mikihiro Takahashi, Hiroyuki Satake, Kensuke Daikoku, Hiroshi Fujii. “Anti-mitochondrial antibody-positive inflammatory myopathy with multiple arrhythmias resistant to high-dose glucocorticoids and intravenous cyclophosphamide: a case-based review” Clin Rheumatol. 2025;44(6):2561-2571.
・Tomoyuki Mutoh (corresponding author), Ryoto Sasaki, Kazuhiro Sakamoto, Masataka Kudo. “Clinical Images: Hairy kidney in IgG4-related disease” Arthritis Rheumatol. 2025;77(9):1273.
・Tomoyuki Mutoh (corresponding author), Hiroshi Nakamura, Hiroshi Fujii. “Scurvy with spontaneous intramuscular hemorrhages” QJM. 2025 Mar 13:hcaf067.
doi: 10.1093/qjmed/hcaf067.


CONFERENCE PRESENTATIONS
2015 April “Features of sleep apnea syndrome in patients with established rheumatoid arthritis”, JCR 2015 Annual Scientific Meeting, Nagoya, Japan
2016 April “Features of polymyositis and dermatomyositis in patients with anti-aminoacyl tRNA synthetase antibodies”, JCR 2016 Annual Scientific Meeting, Yokohama, Japan
2018 April “Insufficient Use of Corticosteroids Results in Higher Relapse in Takayasu Arteritis”, JCR 2018 Annual Scientific Meeting, Tokyo, Japan
2018 October “Insufficient Use of Corticosteroids Results in Higher Relapse in Takayasu Arteritis”, 2018 ACR/ARHP Annual Meeting, Chicago, USA
2019 April “Endothelial protein C receptor and scavenger receptor class B type 1 are major autoantigens in Takayasu arteritis”, JCR 2019 Annual Scientific Meeting, Kyoto, Japan
2019 July “Endothelial protein C receptor and scavenger receptor class B type 1 are major autoantigens in Takayasu arteritis”, JCR International School 2019, Karuizawa, Japan
2019 November “Endothelial Protein C Receptor and Scavenger Receptor Class B Type 1 Negatively Regulate Vascular Inflammation and Are Major Autoantigens in Takayasu Arteritis”, 2019 ACR/ARHP Annual Meeting, Atlanta, USA
2020 August-September “Pathogenic potential of novel autoantibodies in Takayasu arteritis”, JCR 2020 Annual Scientific Meeting, Japan
2021 April-May “Study on long-term retention rate of golimumab treatment for rheumatoid arthritis”, JCR 2021 Annual Scientific Meeting, Kobe, Japan
2021 April-May “A case of refractory eosinophilic granulomatosis with polyangiitis successfully treated with cyclophosphamide, rituximab, and mepolizumab”, JCR 2021 Annual Scientific Meeting, Kobe, Japan

HONORS AND AWARDS
2014 Initial training physicians Plenary sessions Young Scientist Award
2019 JCR 2019 ICW Excellent Abstract Award
2020 JCR 2020 ICW Excellent Abstract Award

ORCID ID

http://orcid.org/0000-0001-5995-8609

Reviewer Keywords
anca-associated vasculitis (aav) idiopathic inflammatory myopathies idiopathic inflammatory myopathy idiopathic inflammatory myositis myositis takayasu arteritis (tak) vasculitides vasculitis
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