Patricia Mesa MD Biography https://delirium-uci.uy/ Patricia Mesa is a Uruguayan MD that works as a coordinating MD of the Pasteur Hospital Intensive Care Unit (ICU). She was an Associate Professor of the Medicine School Intensive Care Department and Assistant Professor of the Pathophysiology Department at the Clínicas Hospital, Montevideo, Uruguay. She has headed the research on delirium in the ICU since 2004. The research studies done include the following: In 2006 the first pilot project carried out at the Clínicas Hospital ICU Department was called Incidence of Delirium in the Critical Patient and its Related Variables. At the same moment, a survey at national level was conducted: Delirium in the Critical Patient: Evaluation of Knowledge in the Health Teams in Uruguay. In 2009 she chaired the Conference Delirium in the ICU. How to recognize and treat it? at the XI Uruguayan Congress of Intensive Medicine. In 2011 at the XIX Congress of Argentinian Intensive Care Unit Society (SATI) she formed together with Previgliano I MD and Wes Ely MD the first work group of delirium in the ICU at regional level, which agreed on the procedures to be used in the delirium research in these countries. In 2013 she created the For an ICU without delirium team and started with educational activities at the Pasteur Hospital ICU. In 2014 the Agitation and Delirium in the ICU study was carried out in the Pasteur Hospital ICU. This project was presented in 2015 at the XIV Uruguayan Congress of Intensive Care Medicine and was granted the First Award to the best scientific work. In 2016 going further with the approach to delirium not only at national level, but also at regional level the integration with the Fernandez Hospital ICU health team headed by Previgliano I MD (Buenos Aires, Argentina) was carried out. In June 2017 she presented two posters at the American Delirium Society 7th Annual Conference: Agitation in the ICU and Delirium in a Latin American ICU A Prospective Cohort in Mechanical Ventilated Patients, and the latter was granted the First Poster Award. In October 2017 Delirium in a Latin American ICU A Prospective Cohort in Mechanical Ventilated Patients paper was published in the Revista Brasilera de Terapia Intensiva. In November 2017 she presented along with Previgliano I MD the work: Delirium Development Associated Factors in two Latin American Intensive Care Units in the XIII World Congress of Critical Care. This was the first regional research on the subject. In June 2018, she presented in the ADS 8th Meeting two posters: For an ICU without Delirium and Delirium in Two Latin American ICUs, (working jointly with Fernandez Hospital, Argentina). At that moment, the Latin American Delirium Interest Group was created. In December 2018 For an ICU without Delirium study was presented at the IV Uruguayan Nursing Congress of Psychiatry and Mental Health and it was granted the Second Award to the Best scientific work. In March 2019 she organized along with the Latin American Delirium Special Interest Group the First Latin American Symposium of Delirium, held in San Pablo, Brazil. In June 2019 she took part of the ADS 9th Annual Meeting in the Roundtable: Delirium Recognition and Reduction: Practices Across the Americas. In July 2019 she took part of the Meeting of experts in delirium around the world, invitation made by the Global Council Brain on Health GCBH (GCBH) and by the American Association Retired Persons (AARP). Sole representative of Latin America. MA; USES; July 31 and August 1, 2019 in Boston, Massachusetts, USA. Objective of this meeting: to make the recommendations Preserving Your Brain Health During Illness or Surgery: Recommendations to Prevent and Treat Delirium. Link: https://www.aarp.org/health/brain-health/global-council-on-brain-health/delirium In September 2019 she had an Interview carried out by the State Health Services Administration Channel to the Pasteur Hospital ́s For an ICU without delirium Team. Link: http://www.asse.com.uy/contenido/Equipo-del-Hospital-Pasteur-reconocido- internacionalmente- por-su-trabajo-y-logros-por-una-Unidad-de-Cuidados-Intensivos- sin-Delirium-11812 In October 2019 she took part at of the Conference Delirium in the critically ill patients, at the postgraduate of Critical Care Medicine Department, Clinical Hospital - Medicine School. https://www.cti.hc.edu.uy In November 2019 she took part of the 16th Intensive Medicine Uruguayan Congress done from October 30th 2019 to November 1st 2019 Roundtable Coordination on ICU Analgesia and Sedation Conference Speaker of Sedation and Delirium on critically ill patients. Presentation of the following research papers Analysis of the variables that influence on delirium in two Lantin American ICU, with different Statistical Tools Férnandez Hospital Buenos Aires, Argentina, Pasteur Hospital Montevideo, Uruguay. Evaluation of the Post Intensive Care Syndrome PICS, cognitive, psychological and physical features and its relationship with ICU delirium. In March 2020, the paper called Preserving your Brain Health During Illness or Surgery: GCBH Recommendations to Prevent and Treat Delirium was published in La Global Council Brain on Health (GCBH) and American Association of Retired Persons (AARP) In October 2020, the POCDE project was chosen to participate in the NIDUS BOOT CAMP (Network Investigation Delirium US) In March 2021, the guidelines for the Hospital Pasteur ICU’s book of protocols: Delirium and Agitation in the ICU were established. In April 2021, “ Core outcome measures for trials in people with COVID-19: respiratory failure, multiorgan failure, shortness of breath and recovery” coauthored by Hospital Pasteur ICU was published in the Critical Care Medicine journal. In June 2021 Virtual American Delirium Society Annual Conference: Poster presented: “Evaluation of the Post Intensive Care Syndrome: Cognitive, Psychological and Physical Aspects and its Relationship with Delirium in the Intensive Care Unit” on Tuesday, June 15, 2021. August 2021: implementation of the education project at national level: POINT OF CARE DELIRIUM EDUCATION (POCDE) Training project at national level, to improve clinical intervention in delirium prevention and treatment. In 2022, the award as the best scientific paper was granted to her in the Uruguayan Congress of Intensive Medicine at work: Delirium as a determining factor of long-term cognitive dysfunction in the intensive post care syndrome. Prospective study in a Latin America Unit. 2022: Best Poster Award: “Is agitation a serious problem in the critical care patient? Prospective study in two phases in a Latin American Intensive Care Unit”.¿Es la agitación un problema grave en el paciente de cuidados críticos. Mesa P., et al. 11th Johns Hopkins. Annual Johns Hopkins Critical Care Rehabilitation Conference, Baltimore, USA. 2023: 13th Annual American Delirium Society Conference, Rhode Island, USA. “Is agitation a Serious problem in the critical care patient?” Prospective study in two phases in a Latin American Intensive Care Unit”. Mesa P. et al. 2024: publications: Mesa, P., & Kotfis K. “Identifying and treating hypoactive delirium: back to square one? Authors' reply”. Intensive Care Med. 2024 Dec 11. PMID: 39661132.Doi: 10.1007/s00134-024-07730-y. 2024: Kotfis, Katarzyna, Patricia Mesa, and Wesley Ely. “How to end quiet suffering in the intensive care unit” Identifying? and treating hypoactive delirium. Intensive Care Medicine (2024): 50(10), 1695–1698. https://doi.org/10.1007/s00134-024-07534-0 2025: publications: Mesa, P., Lecor, C., Orellano, M. E., Favretto, S., Altez, S., Da Luz, J., ... & Pontet, J. (2025). Evaluación del impacto de intervenciones educativas en la detección y el diagnóstico del delirium en una unidad de cuidados intensivos. Revista Médica del Uruguay, 41(1). https://doi.org/10.29193/rmu.41.1.2. 2025: Mesa, P., Gutiérrez, I., Lecor, C., Orellano, M. E., Favretto, S., Altez, S., Da Luz, J., ... & Pontet, J. (2025). Agitación en la unidad de cuidados intensivos: evaluación de su incidencia, factores de riesgo y consecuencias antes y después de la implementación de un programa educativo. https://doi.org/10.29193/RMU.41.2.7. 2025: Mesa P, Kotfis K, Lecor C, et al. (March 14, 2025) Delirium as a Determinant of Long-Term Cognitive Dysfunction in the Context of Post-intensive Care Syndrome: A Prospective Study in a Latin American Environment. Cureus 17(3): e80578.doi:10.7759/cureus.80578.https://www.cureus.com/articles/335253-delirium-as-a-determinant- of-long-term-cognitive-dysfunction-in-the-context-of-post-intensive- care-syndrome-a-prospective-study-in-a-latin-american-environment