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Avanafil is a highly selective, potent, reversible inhibitor of cyclic guanosine monophosphate (cGMP) - a specific phosphodiesterase type 5 (PDE-5). Buy it online to get a cure for Erectile dysfunction. When sexual arousal causes local release of nitric oxide, PDE5 inhibition by avanafil increases cGMP levels in the corpora cavernosa of the penis. This leads to relaxation of smooth muscles and blood flow to the tissues of the penis, resulting in an erection. Avanafil is ineffective in the absence of sexual stimulation.
