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One notable feature of the synthetic opioid analgesic Tramadol is its dual mechanism of action, which combines inhibition of serotonin and norepinephrine reuptake with mu-opioid receptor binding. This special combination offers potential advantages for managing neuropathic pain in addition to providing efficient pain relief. Though less so than with conventional opioids, tramadol still carries some risks, such as the possibility of dependence and abuse in addition to adverse effects like nausea, vertigo, and constipation. Tramadol is a useful option for pain management strategies that requires careful consideration and individualized treatment plans to balance its potential benefits and drawbacks.

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