Cureus
Floyd Nathan
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Inhibition of Serotonin and Norepinephrine Reuptake: Tramadol increases the levels of serotonin and norepinephrine in the brain, neurotransmitters that play a key role in mood and pain perception. This action not only enhances its pain-relieving effects but also contributes to a mood lift, which can be beneficial for patients dealing with chronic pain.

Tramadol Interactions
When incorporating Tramadol into your pain management plan, it’s crucial to be aware of potential interactions with other medications, which can alter its effectiveness or increase the risk of side effects. Key interactions include:

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