Cureus
Helths Benefits
Create your FREE profile now!

Join the discussion with physicians and researchers around the globe - sign up for your free Cureus account today.

ADVERTISEMENT
About

Tramadol is a synthetic opioid analgesic medication used to treat moderate to moderately severe pain in adults. It works by changing the way the brain and nervous system respond to pain. As part of a class of drugs known as opioid agonists, Tramadol is similar to endorphins – the brain's natural pain reducers – by binding to receptors in the brain to decrease the body's perception of pain.

Mechanism of Action

Tramadol operates through two main mechanisms: it binds to the μ-opioid receptor on nerve cells (which are involved in the transmission of pain sensations throughout the body) and also inhibits the reuptake of two neurotransmitters, serotonin and norepinephrine, which are involved in mood and response to pa

ADVERTISEMENT