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Suboxone is administered as a sublingual film, meaning it is placed under the tongue to dissolve. Keep in mind that it usually takes two days after you start taking Suboxone for the correct dose to enter your body. During this time you may experience hunger or withdrawal symptoms. Suboxone is a prescription medication used to treat opioid addiction in adults. It is part of a comprehensive treatment plan for opioid use disorder (OUD). Suboxone contains two active ingredients: buprenorphine and naloxone. These medications work together to prevent withdrawal symptoms caused by stopping opioid use.