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10mg Oxycodone is a semisynthetic pure opioid agonist whose principal therapeutic action is analgesia. Other pharmacological effects of oxycodone include anxiolysis, euphoria, and feelings of relaxation. These effects are mediated by receptors in the central nervous system for endogenous opioid-like compounds such as endorphins and enkephalins. Oxycodone 10 mg produces respiratory depression through direct activity at respiratory centers in the brain stem and depresses the cough reflex with a direct effect on the center of the medulla.