Dr. Saif is Professor of Medicine at Tufts Medical school and the Director, Gastrointestinal Oncology Program and Leader, Experimental Therapeutics Program at the Tufts Medical Center, Boston.Dr. Saif specializes in caring for patients with GI malignancies, in particular pancreatic cancer and colorectal cancer. His expertise lies in research focused on the biochemical and molecular pharmacology of antimetabolites and investigational anticancer agents in an effort to develop therapeutic strategies for patients with cancers arising in the gastrointestinal tract as well as other solid tumors resistant to traditional treatment.  

Dr. Saif graduated from King Edward Medical University, Lahore, Pakistan. Following an internal medicine residency at the University Of Connecticut School Of Medicine, Farmington, CT; a medical oncology fellowship at the National Cancer Institute, NIH, Bethesda, MD and the National Naval Medical Center, Bethesda, MD; and a hematology fellowship at the National Heart, Lung, and Blood Institute (NHLBI), NIH, Bethesda. After the clinical fellowship, he became a junior investigator in the Investigational Drug Branch, NCI where he worked in the Gastrointestinal Malignancies Section.

Prior to joining Tufts, he was the Professor of Clinical Medicine, Division of Hematology/Oncology, Department of Medicine, Director of the GI Oncology Section of the Division of Hematology/Oncology at the Herbert Irving Comprehensive Cancer Center (HICCC), at Columbia University, College of Physicians and Surgeons, and the Medical Director of the Pancreas Center at the New York-Presbyterian Hospital. Columbia University College of Physicians and Surgeons, Herbert Irving Cancer Center and the New York Presbyterian Hospital. Dr. Saif also worked at the University of Alabama at Birmingham (UAB) as an Assistant Professor of Medicine and Pharmacology and the Yale School of Medicine, New Haven as an Associate professor of Medicine, Director of GI Cancers Program and Senior Investigator in the Department of Developmental Therapeutics.

Dr. Saif is recognized as an internationally renowned expert in GI cancers and developmental/experimental therapeutics.  He is a member of the American Society of Clinical Oncology, American Society for Pharmacology and Experimental Therapeutics, and many others. He has published over 500 peer-reviewed articles about cancer treatment and research and over 70 abstracts, and 21 book chapters, beginning in 1997 and continuing to present.  He serves on the editorial board of over 23 peer reviewed cancer journals.

Dr. Saif was chosen by his peers as one of the America's top Oncologist for the last consecutive 5 years and also was recently considered among the top 5% phyisicnas in USA.