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Melanie H. Gephart
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About

As a practicing neurosurgeon, my daily interactions with neuro-oncology patients uniquely positions our lab to focus on translational neuro-oncology research, combining basic neuroscience, genetics, and tumor biology, with an unique insight into the pressing clinical questions facing patients with brain tumors. My postdoctoral fellowship in the lab of Dr. Matthew Scott focused on the cellular mechanisms underlying the genetics and tumor biology of medulloblastoma. My masters degree in clinical research provides insight into the translation potential of newly identified treatments through development of clinical trials. In this way, we bridge laboratory bench research into viable therapeutics for patients with brain tumors. Our ongoing investigations into tumor cell biology, developmental neuroscience, cell signal transduction, and translational preliminary studies of novel therapeutics each feedback into and exponentially advance the field of neuro-oncology. Our discoveries in the lab will develop into hypotheses about novel treatment and diagnostic development, and working with patients and primary samples develops questions for the lab regarding tumor cell biology and normal neurodevelopment.


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Publications (6)

Recent article categories: Radiation Oncology, Neurosurgery

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Co-authors (21)
Zachary Medress Medical Student
Neurological Surgery
2 co-publications

Kevin Kwong-Hon Chow M.D. Ph.D.
Neurological Surgery
1 co-publications

Jennifer Ziskin None
Pathology
1 co-publications

Hannes Vogel None
Neurology
1 co-publications

Gordon H. Li M.D.
Neurological Surgery
1 co-publications

Adrienne M. Moraff
Neurological Surgery
1 co-publications

Larry M. Shuer M.D.
Neurological Surgery
1 co-publications

Jeremy J. Heit
Radiology
1 co-publications

Robert T. Arrigo
Anesthesiology
1 co-publications

Corinna C. Zygourakis
Neurological Surgery
1 co-publications

Maxwell Boakye M.D. M.P.H. Professor
Neurological Surgery
1 co-publications

Ian D. Connolly
Ian D. Connolly Medical Student
Neurological Surgery
1 co-publications

Eli Johnson
Eli Johnson
Neurological Surgery
1 co-publications

Seth Lummus
Seth Lummus
Pathology
1 co-publications

Sayantan  Deb
Sayantan Deb
Neurological Surgery
1 co-publications

Daivik B. Vyas
Daivik B. Vyas
Neurological Surgery
1 co-publications

Arjun V. Pendharkar
Arjun V. Pendharkar M.D. Resident Physician
Neurological Surgery
1 co-publications

Paymon G. Rezaii
Paymon G. Rezaii M.Sc.
Neurological Surgery
1 co-publications

Matthew K. Schoen
Matthew K. Schoen
Neurological Surgery
1 co-publications

Kaniksha Desai
Kaniksha Desai
Internal Medicine: Diabetes and Endocrinology
1 co-publications

Atman Desai
Atman Desai
Neurological Surgery
1 co-publications