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Melanie H. Gephart
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As a practicing neurosurgeon, my daily interactions with neuro-oncology patients uniquely positions our lab to focus on translational neuro-oncology research, combining basic neuroscience, genetics, and tumor biology, with an unique insight into the pressing clinical questions facing patients with brain tumors. My postdoctoral fellowship in the lab of Dr. Matthew Scott focused on the cellular mechanisms underlying the genetics and tumor biology of medulloblastoma. My masters degree in clinical research provides insight into the translation potential of newly identified treatments through development of clinical trials. In this way, we bridge laboratory bench research into viable therapeutics for patients with brain tumors. Our ongoing investigations into tumor cell biology, developmental neuroscience, cell signal transduction, and translational preliminary studies of novel therapeutics each feedback into and exponentially advance the field of neuro-oncology. Our discoveries in the lab will develop into hypotheses about novel treatment and diagnostic development, and working with patients and primary samples develops questions for the lab regarding tumor cell biology and normal neurodevelopment.

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Reviewer Rating

Publications (6)

Recent article categories: Radiation Oncology, Neurosurgery

Co-authors (21)
Zachary Medress Medical Student
Neurological Surgery

Kevin Kwong-Hon Chow M.D. Ph.D.
Neurological Surgery

Jennifer Ziskin None

Hannes Vogel None

Gordon H. Li M.D.
Neurological Surgery

Adrienne M. Moraff
Neurological Surgery

Larry M. Shuer M.D.
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Jeremy J. Heit Ph.D. M.D.

Robert T. Arrigo

Corinna C. Zygourakis
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Maxwell Boakye M.D. M.P.H. Professor
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Ian D. Connolly Medical Student
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Eli Johnson
Neurological Surgery

Seth Lummus

Sayantan Deb
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Daivik B. Vyas
Neurological Surgery

Arjun V. Pendharkar M.D. Resident Physician
Neurological Surgery

Paymon G. Rezaii M.Sc.
Neurological Surgery

Matthew K. Schoen
Neurological Surgery

Kaniksha Desai
Internal Medicine: Diabetes and Endocrinology

Atman Desai
Neurological Surgery