I am a PHYSICIAN SCIENTIST:
I specialize in medical outcomes research – systematic reviews & meta-analyses. I have a rare combination of complex research abilities and clinical skills as an internal medicine physician.
With my exceptional skills as a physician, I am able to understand the clinical problems, frame relevant clinical questions that would improve patient care, and personally able to perform clinical research (meta-analysis and systematic reviews) trying to answer these questions.
This allows me to obtain more definitive results to provide answers for these clinical problems. These results provide high quality evidence that would support the nationwide influence and implementation of the intervention. In turn, this can improve patient outcomes and reduce healthcare costs throughout USA and worldwide.

I have co authored multiple publications:A systematic review and meta-analysis of randomized controlled trials: Efficacy and safety of larazotide acetate in celiac disease patients undergoing a gluten challenge. Moole H, Patel P, Dharmapuri D, Boddireddy R, Moole V, Yedama P, Bondalapati N, Uppu A, Yerasi C. Gastroenterol Pancreatol Liver Disord.2016 Jun; 3(1): 1-8.
Association of clinical signs and symptoms of Ebola viral disease with case fatality: a systematic review and meta-analysis. Moole H, Chitta S, Victor D, Kandula M, Moole V, Ghadiam H, Akepati A, Yerasi C, Uppu A, Dharmapuri S, Boddireddy R, Fischer J, Lynch T. J Community Hosp Intern Med Perspect. 2015 Sep 1;5(4):28406. doi: 10.3402/jchimp.v5.28406. eCollection 2015. PMID: 26333864.
Harsha Moole, Charan Yerasi, Vishnu Moole, Sowmya Dharmapuri, Achuta Uppu: Sa1815 A Systematic Review and Meta-Analysis of Randomized Controlled Trials: Improvement in Endoscopic Disease Activity of Ulcerative Colitis With Curcumin Treatment. Gastrointestinal Endoscopy 04/2016; 83(5s). DOI:10.1016/j.gie. 2016.03.465

Harsha Moole, Anushi Shah, Raghuveer R. Boddireddy, Vishnu Moole, Achuta Uppu: Sa1647 Comparison of Survival Rates and Morbidity With Norepinephrine Plus Albumin Versus Terlipressin Plus Albumin Therapy in Treating Hepatorenal Syndrome: A Systematic Review and Meta-Analysis. Gastroenterology 04/2016; 150(4). DOI:10.1016/S0016-5085(16)33661-7
Harsha Moole, Achuta Uppu, Raghuveer R. Boddireddy, Vishnu Moole, Sowmya Dharmapuri, Charan Yerasi: Sa1590 A Systematic Review and Meta-Analysis of Randomized Trials: Terlipressin Related Survival Benefit and Adverse Events in Treating Hepatorenal Syndrome. Gastroenterology 04/2016; 150(4). DOI: 10.1016/S0016-5085(16)31180-5
Harsha Moole, Anushi Shah, Raghuveer R. Boddireddy, Vishnu Moole, Achuta Uppu: Sa1589 Comparing the Efficacy of Norepinephrine Plus Albumin Versus Terlipressin Plus Albumin in Treating Hepatorenal Syndrome: A Systematic Review and Meta- Analysis. Gastroenterology 04/2016; 150(4). DOI:10.1016/ S0016-5085(16)31179-9
Harsha Moole, Raghuveer R. Boddireddy, Vishnu Moole, Charan Yerasi, Sowmya Dharmapuri, Achuta Uppu: Mo1500 Complications Associated With Photodynamic Therapy in Palliation of Unresectable Cholangiocarcinoma: A Systematic Review and Meta- Analysis. Gastroenterology 04/2016; 150(4). DOI:10.1016/ S0016-5085(16)33822-7
Systematic Review and Meta-analysis of Randomized Trials: Curcumin Treatment for Clinical Remission Induction in Patients with Mild to Moderate Ulcerative Colitis. Harsha Moole, MD1, Sahitya Settypalli, MD1, Sowmya Dharmapuri, MBBS2, Raghuveer Boddireddy, MBBS2, Vishnu Moole, MBBS2, Pratyusha Yedma, MBBS2, Naveen Bondalapati, MD3, Achuta Uppu, MD4, Abhiram Duvvuri, MD5, Zohair Ahmed, MD1. American Journal of Gastroenterology 10/2016; Supp; P1377
A Meta-Analysis and Systematic Review: Comparing Mortality and Morbidity of Endoscopic versus Percutaneous Approach in Palliation of Advanced Hilar Malignancies. Harsha Moole, MD 1, Sirish Dharmapuri, MD2, Sowmya Dharmapuri, MBBS3, Raghuveer Boddireddy, MBBS3, Vishnu Moole, MBBS3, Pratyusha Yedma, MBBS3, Naveen Bondalapati, MD4, Achuta Uppu, MD5, Abhiram

Duvvuri, MD6, Harsha Tathireddy, MD7. American Journal of Gastroenterology 10/2016; Supp; P1378
Endoscopic vs Percutaneous Approach for Successful Biliary Drainage in Palliation of Advanced Hilar Malignancies: A Meta- Analysis and Systematic Review. Harsha Moole, MD 1, Sirish Dharmapuri, MD2, Sowmya Dharmapuri, MBBS3, Raghuveer Boddireddy, MBBS3, Vishnu Moole, MBBS3, Pratyusha Yedma, MBBS3, Naveen Bondalapati, MD4, Achuta Uppu, MD5, Abhiram Duvvuri, MD6, Harsha Tathireddy, MD7. American Journal of Gastroenterology 10/2016; Supp; P1538
Clinical improvement in eosinophilic esophagitis patients treated with endoscopicesophageal dilation: A meta-analysis and systematic review. Kavitha Jacob, MD1, Harsha Moole, MD1Vishnu Moole, MBBS2, Sowmya Dharmapuri, MBBS2, Raghuveer Boddireddy, MBBS2, Prathyusha Yedama, MBBS2, Naveen Bondalapati, MD3, Achuta Uppu, MD4, Abhiram Duvvuri, MD5, Srinivas Puli, MD6. American Journal of Gastroenterology 10/2016; Supp; P
A meta-analysis and systematic review: Is endoscopic esophageal dilation a safe approach in managing eosinophilic esophagitis? Kavitha Jacob, MD1, Harsha Moole, MD1, Vishnu Moole, MBBS2, Sowmya Dharmapuri, MBBS2, Raghuveer Boddireddy, MBBS2, Prathyusha Yedama, MBBS2, Naveen Bondalapati, MD3, Achuta Uppu, MD4, Abhiram Duvvuri, MD5, Srinivas Puli, MD6. American Journal of Gastroenterology 10/2016; Supp; P
Harsha Moole, Charan Yerasi, Vishnu Moole, Sowmya Dharmapuri, Achuta Uppu: Sa1815 A Systematic Review and Meta-Analysis of Randomized Controlled Trials: Improvement in Endoscopic Disease Activity of Ulcerative Colitis With Curcumin Treatment. DDW 2016 International conference, San Diego, California.
Harsha Moole, Anushi Shah, Raghuveer R. Boddireddy, Vishnu Moole, Achuta Uppu: Sa1647 Comparison of Survival Rates and Morbidity With Norepinephrine Plus Albumin Versus Terlipressin Plus Albumin Therapy in Treating Hepatorenal Syndrome: A Systematic Review and Meta-Analysis. DDW 2016 International conference, San Diego, California.
Harsha Moole, Achuta Uppu, Raghuveer R. Boddireddy, Vishnu Moole, Sowmya Dharmapuri, Charan Yerasi: Sa1590 A Systematic Review and Meta-Analysis of Randomized Trials: Terlipressin

Related Survival Benefit and Adverse Events in Treating Hepatorenal Syndrome. DDW 2016 International conference, San Diego, California.
Harsha Moole, Anushi Shah, Raghuveer R. Boddireddy, Vishnu Moole, Achuta Uppu: Sa1589 Comparing the Efficacy of Norepinephrine Plus Albumin Versus Terlipressin Plus Albumin in Treating Hepatorenal Syndrome: A Systematic Review and Meta- Analysis. DDW 2016 International conference, San Diego, California.
Harsha Moole, Raghuveer R. Boddireddy, Vishnu Moole, Charan Yerasi, Sowmya Dharmapuri, Achuta Uppu: Mo1500 Complications Associated With Photodynamic Therapy in Palliation of Unresectable Cholangiocarcinoma: A Systematic Review and Meta- Analysis. DDW 2016 International conference, San Diego, California.
Systematic Review and Meta-analysis of Randomized Trials: Curcumin Treatment for Clinical Remission Induction in Patients with Mild to Moderate Ulcerative Colitis. Harsha Moole, MD1, Sahitya Settypalli, MD1, Sowmya Dharmapuri, MBBS2, Raghuveer Boddireddy, MBBS2, Vishnu Moole, MBBS2, Pratyusha Yedma, MBBS2, Naveen Bondalapati, MD3, Achuta Uppu, MD4, Abhiram Duvvuri, MD5, Zohair Ahmed, MD1. ACG International Conference 2016, Las Vegas, Nevada
A Meta-Analysis and Systematic Review: Comparing Mortality and Morbidity of Endoscopic versus Percutaneous Approach in Palliation of Advanced Hilar Malignancies. Harsha Moole, MD 1, Sirish Dharmapuri, MD2, Sowmya Dharmapuri, MBBS3, Raghuveer Boddireddy, MBBS3, Vishnu Moole, MBBS3, Pratyusha Yedma, MBBS3, Naveen Bondalapati, MD4, Achuta Uppu, MD5, Abhiram Duvvuri, MD6, Harsha Tathireddy, MD7. ACG International Conference 2016, Las Vegas, Nevada
Clinical improvement in eosinophilic esophagitis patients treated with endoscopicesophageal dilation: A meta-analysis and systematic review. Kavitha Jacob, MD1, Harsha Moole, MD1Vishnu Moole, MBBS2, Sowmya Dharmapuri, MBBS2, Raghuveer Boddireddy, MBBS2, Prathyusha Yedama, MBBS2, Naveen Bondalapati, MD3, Achuta Uppu, MD4, Abhiram Duvvuri, MD5, Srinivas Puli, MD6. ACG International Conference 2016, Las Vegas, Nevada
A meta-analysis and systematic review: Is endoscopic esophageal dilation a safe approach in managing eosinophilic esophagitis?

Kavitha Jacob, MD1, Harsha Moole, MD1, Vishnu Moole, MBBS2, Sowmya Dharmapuri, MBBS2, Raghuveer Boddireddy, MBBS2, Prathyusha Yedama, MBBS2, Naveen Bondalapati, MD3, Achuta Uppu, MD4, Abhiram Duvvuri, MD5, Srinivas Puli, MD6. ACG International Conference 2016, Las Vegas, Nevada