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The Barcellos-Hoff laboratory studies radiation carcinogenesis and biologically augmented radiotherapy. Dr. Barcellos-Hoff received an undergraduate degree from the University of Chicago and earned a doctoral degree in experimental pathology from the University of California, San Francisco. She conducted postdoctoral research on extracellular matrix mediated functional differentiation with Mina Bissell at the Lawrence Berkeley National Laboratory (LBNL). She joined LBNL as a staff scientist, where she rose from postdoctoral fellow to Senior Scientist and Associate Director of the Life Sciences Division. She joined New York University School of Medicine in 2008 as Director of Radiation Biology in the Department of Radiation Oncology. She moved to UCSF as Professor and Vice Chair of Research in the Department of Radiation Oncology in 2015.