Case Report
Reversible Splenium Lesion of the Corpus Callosum in Hemorrhagic Fever with Renal Failure Syndrome
Shin-Hye Baek, Dong-Ick Shin, Hyung-Suk Lee, Sung-Hyun Lee, Hye-Young Kim, Kyeong Seob Shin, Seung Young Lee, Ho-Seong Han, Hyun Jeong Han, Sang-Soo Lee
Published:
August 01, 2010
DOI:
10.3346/jkms.2010.25.8.1244
License:
© 2010 The Korean Academy of Medical Sciences.2010This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
This is the first case of virus-associated encephalitis/encephalopathy in which the pathogen was Hantaan virus. A 53-yr-old man presented fever, renal failure and a hemorrhagic tendency and he was diagnosed with hemorrhagic fever with renal failure syndrome (HFRS). In the course of his illness, mild neurologic symptoms such as dizziness and confusion developed and magnetic resonance images revealed a reversible lesion in the splenium of the corpus callosum. This case suggests that HFRS patients with neurologic symptoms like dizziness and mental slowing should be considered to have structural brain lesions and to require brain imaging studies.