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Case report
peer-reviewed

Case of Enteric Fever with Bicytopenia



Abstract

Infectious diseases are one of the major causes of morbidity and mortality in developing countries. Typhoid has its own contribution to the disease burden, especially in Pakistan and other tropical countries. Herein, we present a case of enteric fever with a rare presentation. Our patient is a 20-year-old man who gradually developed high-grade fever lasting seven days associated with rigors and chills. No additional accompanying systemic signs helped to localize the infection. After extensive laboratory testing, his typhoid serology was positive along with leukocytopenia and thrombocytopenia. Typhoid fever is typically associated with either diarrhea or constipation and sphygmothermic dissociation (Faget’s sign); our patient did not have these symptoms or signs. As leukocytopenia and thrombocytopenia contribute to mortality and complications, it was necessary to monitor the patient accordingly.



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Case report
peer-reviewed

Case of Enteric Fever with Bicytopenia


Author Information

Madeeha Subhan Corresponding Author

Capital Hospital Islamabad, Ayub Teaching Hospital, Abbottabad

Waleed Sadiq

Department of Medicine, Shifa International Hospital


Ethics Statement and Conflict of Interest Disclosures

Human subjects: Consent was obtained by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.


Case report
peer-reviewed

Case of Enteric Fever with Bicytopenia


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Case report
peer-reviewed

Case of Enteric Fever with Bicytopenia

Madeeha Subhan">Madeeha Subhan , Waleed Sadiq">Waleed Sadiq

  • Author Information
    Madeeha Subhan Corresponding Author

    Capital Hospital Islamabad, Ayub Teaching Hospital, Abbottabad

    Waleed Sadiq

    Department of Medicine, Shifa International Hospital


    Ethics Statement and Conflict of Interest Disclosures

    Human subjects: Consent was obtained by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

    Acknowledgements


    Article Information

    Published: December 06, 2017

    DOI

    10.7759/cureus.1910

    Cite this article as:

    Subhan M, Sadiq W (December 06, 2017) Case of Enteric Fever with Bicytopenia . Cureus 9(12): e1910. doi:10.7759/cureus.1910

    Publication history

    Received by Cureus: November 22, 2017
    Peer review began: November 30, 2017
    Peer review concluded: November 30, 2017
    Published: December 06, 2017

    Copyright

    © Copyright 2017
    Subhan et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 3.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

    License

    This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Infectious diseases are one of the major causes of morbidity and mortality in developing countries. Typhoid has its own contribution to the disease burden, especially in Pakistan and other tropical countries. Herein, we present a case of enteric fever with a rare presentation. Our patient is a 20-year-old man who gradually developed high-grade fever lasting seven days associated with rigors and chills. No additional accompanying systemic signs helped to localize the infection. After extensive laboratory testing, his typhoid serology was positive along with leukocytopenia and thrombocytopenia. Typhoid fever is typically associated with either diarrhea or constipation and sphygmothermic dissociation (Faget’s sign); our patient did not have these symptoms or signs. As leukocytopenia and thrombocytopenia contribute to mortality and complications, it was necessary to monitor the patient accordingly.



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Madeeha Subhan, MBBS

Capital Hospital Islamabad, Ayub Teaching Hospital, Abbottabad

For correspondence:
madeehas99@gmail.com

Waleed Sadiq, M.D.

Department of Medicine, Shifa International Hospital

Madeeha Subhan, MBBS

Capital Hospital Islamabad, Ayub Teaching Hospital, Abbottabad

For correspondence:
madeehas99@gmail.com

Waleed Sadiq, M.D.

Department of Medicine, Shifa International Hospital