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Case report
peer-reviewed

Rhino-Orbital-Cerebral Mucormycosis: A Fatal Complication of Uncontrolled Diabetes Mellitus



Abstract

Mucormycosis is a progressively invasive disease, with a fatal outcome, on late presentation. A 38-year-old female presented with diabetic ketoacidosis with right eye ptosis and a frozen globe without any signs of inflammation, externally. She underwent transnasal endoscopic debridement of paranasal sinuses and exenteration of the right eye. The histopathology specimen revealed the growth of mucormycosis. She was treated with intravenous (IV) amphotericin B, IV insulin, and extensive debridement surgery, but had an unfavorable outcome due to rapid mucor invasion to the brain.



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Case report
peer-reviewed

Rhino-Orbital-Cerebral Mucormycosis: A Fatal Complication of Uncontrolled Diabetes Mellitus


Author Information

Purva Bavikar

Resident, Department of Internal Medicine, MGM Medical College, Navi Mumbai, India

Varshil Mehta Corresponding Author

Department of Internal Medicine, MGM Medical College, Navi Mumbai, India

Department of Cardiology, Mount Sinai Hospital, New York, USA

Editorial Board Member, Cureus


Ethics Statement and Conflict of Interest Disclosures

Human subjects: Consent was obtained by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.


Case report
peer-reviewed

Rhino-Orbital-Cerebral Mucormycosis: A Fatal Complication of Uncontrolled Diabetes Mellitus


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Case report
peer-reviewed

Rhino-Orbital-Cerebral Mucormycosis: A Fatal Complication of Uncontrolled Diabetes Mellitus

Purva Bavikar">Purva Bavikar, Varshil Mehta">Varshil Mehta

  • Author Information
    Purva Bavikar

    Resident, Department of Internal Medicine, MGM Medical College, Navi Mumbai, India

    Varshil Mehta Corresponding Author

    Department of Internal Medicine, MGM Medical College, Navi Mumbai, India

    Department of Cardiology, Mount Sinai Hospital, New York, USA

    Editorial Board Member, Cureus


    Ethics Statement and Conflict of Interest Disclosures

    Human subjects: Consent was obtained by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

    Acknowledgements


    Article Information

    Published: November 13, 2017

    DOI

    10.7759/cureus.1841

    Cite this article as:

    Bavikar P, Mehta V (November 13, 2017) Rhino-Orbital-Cerebral Mucormycosis: A Fatal Complication of Uncontrolled Diabetes Mellitus. Cureus 9(11): e1841. doi:10.7759/cureus.1841

    Publication history

    Received by Cureus: November 03, 2017
    Peer review began: November 09, 2017
    Peer review concluded: November 10, 2017
    Published: November 13, 2017

    Copyright

    © Copyright 2017
    Bavikar et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 3.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

    License

    This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Mucormycosis is a progressively invasive disease, with a fatal outcome, on late presentation. A 38-year-old female presented with diabetic ketoacidosis with right eye ptosis and a frozen globe without any signs of inflammation, externally. She underwent transnasal endoscopic debridement of paranasal sinuses and exenteration of the right eye. The histopathology specimen revealed the growth of mucormycosis. She was treated with intravenous (IV) amphotericin B, IV insulin, and extensive debridement surgery, but had an unfavorable outcome due to rapid mucor invasion to the brain.



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Create a free account to continue reading this article.

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Purva Bavikar

Resident, Department of Internal Medicine, MGM Medical College, Navi Mumbai, India

Varshil Mehta

Department of Internal Medicine, MGM Medical College, Navi Mumbai, India

For correspondence:
varshil91@gmail.com

Purva Bavikar

Resident, Department of Internal Medicine, MGM Medical College, Navi Mumbai, India

Varshil Mehta

Department of Internal Medicine, MGM Medical College, Navi Mumbai, India

For correspondence:
varshil91@gmail.com