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Case report
peer-reviewed

Salvage Stereotactic Radiosurgery for Multiple Brain Recurrences: How Much is Enough?



Abstract

Stereotactic radiosurgery (SRS) can be used as a salvage treatment in selected patients with recurrent brain metastases after previous brain radiation. We report the case of a patient with metastatic lung adenocarcinoma who experienced recurrence numerous times in the brain and was successfully treated each time with SRS. For this patient, brain imaging surveillance helped identify metastases early for salvage SRS. We have also included a discussion of published literature regarding the neurocognitive toxicity of repeated courses of SRS.



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Case report
peer-reviewed

Salvage Stereotactic Radiosurgery for Multiple Brain Recurrences: How Much is Enough?


Author Information

Fred Hsu Corresponding Author

Radiation Oncology, BC Cancer Agency – Abbotsford Centre


Ethics Statement and Conflict of Interest Disclosures

Human subjects: Consent was obtained by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.


Case report
peer-reviewed

Salvage Stereotactic Radiosurgery for Multiple Brain Recurrences: How Much is Enough?


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Case report
peer-reviewed

Salvage Stereotactic Radiosurgery for Multiple Brain Recurrences: How Much is Enough?

Fred Hsu">Fred Hsu

  • Author Information
    Fred Hsu Corresponding Author

    Radiation Oncology, BC Cancer Agency – Abbotsford Centre


    Ethics Statement and Conflict of Interest Disclosures

    Human subjects: Consent was obtained by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

    Acknowledgements


    Article Information

    Published: November 10, 2017

    DOI

    10.7759/cureus.1835

    Cite this article as:

    Hsu F (November 10, 2017) Salvage Stereotactic Radiosurgery for Multiple Brain Recurrences: How Much is Enough?. Cureus 9(11): e1835. doi:10.7759/cureus.1835

    Publication history

    Received by Cureus: October 10, 2017
    Peer review began: October 20, 2017
    Peer review concluded: November 02, 2017
    Published: November 10, 2017

    Copyright

    © Copyright 2017
    Hsu. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 3.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

    License

    This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Stereotactic radiosurgery (SRS) can be used as a salvage treatment in selected patients with recurrent brain metastases after previous brain radiation. We report the case of a patient with metastatic lung adenocarcinoma who experienced recurrence numerous times in the brain and was successfully treated each time with SRS. For this patient, brain imaging surveillance helped identify metastases early for salvage SRS. We have also included a discussion of published literature regarding the neurocognitive toxicity of repeated courses of SRS.



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Create a free account to continue reading this article.

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Fred Hsu

Radiation Oncology, BC Cancer Agency – Abbotsford Centre

For correspondence:
fhsu@bccancer.bc.ca

Fred Hsu

Radiation Oncology, BC Cancer Agency – Abbotsford Centre

For correspondence:
fhsu@bccancer.bc.ca