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Case report
peer-reviewed

A Full-Blown Case of Bronchiectasis: Kartagener Syndrome Without Infertility Diagnosed Later in Life



Abstract

Kartagener syndrome (KS) is a rare autosomal recessive genetic ciliary disorder characterized by situs inversus, chronic sinusitis, bronchiectasis, and infertility. KS is associated with ultrastructural anomalies of the cilia in epithelial cells covering the upper and lower respiratory tracts and spermatozoa flagella. This case describes a patient with KS with situs inversus and sudden onset bronchiectasis with a sharp decline in respiratory function presenting later in life but without sinusitis or infertility.



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Case report
peer-reviewed

A Full-Blown Case of Bronchiectasis: Kartagener Syndrome Without Infertility Diagnosed Later in Life


Author Information

Madeeha Subhan Corresponding Author

Capital Hospital Islamabad, Ayub Teaching Hospital, Abbottabad

Waleed Sadiq

Department of Medicine, Shifa International Hospital


Ethics Statement and Conflict of Interest Disclosures

Human subjects: Consent was obtained by all participants in this study. Conflicts of interest: The authors have declared that no conflicts of interest exist.


Case report
peer-reviewed

A Full-Blown Case of Bronchiectasis: Kartagener Syndrome Without Infertility Diagnosed Later in Life


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Case report
peer-reviewed

A Full-Blown Case of Bronchiectasis: Kartagener Syndrome Without Infertility Diagnosed Later in Life

  • Author Information
    Madeeha Subhan Corresponding Author

    Capital Hospital Islamabad, Ayub Teaching Hospital, Abbottabad

    Waleed Sadiq

    Department of Medicine, Shifa International Hospital


    Ethics Statement and Conflict of Interest Disclosures

    Human subjects: Consent was obtained by all participants in this study. Conflicts of interest: The authors have declared that no conflicts of interest exist.

    Acknowledgements


    Article Information

    Published: September 11, 2017

    DOI

    10.7759/cureus.1678

    Cite this article as:

    Subhan M, Sadiq W (September 11, 2017) A Full-Blown Case of Bronchiectasis: Kartagener Syndrome Without Infertility Diagnosed Later in Life. Cureus 9(9): e1678. doi:10.7759/cureus.1678

    Publication history

    Received by Cureus: August 24, 2017
    Peer review began: September 03, 2017
    Peer review concluded: September 03, 2017
    Published: September 11, 2017

    Copyright

    © Copyright 2017
    Subhan et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 3.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

    License

    This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Kartagener syndrome (KS) is a rare autosomal recessive genetic ciliary disorder characterized by situs inversus, chronic sinusitis, bronchiectasis, and infertility. KS is associated with ultrastructural anomalies of the cilia in epithelial cells covering the upper and lower respiratory tracts and spermatozoa flagella. This case describes a patient with KS with situs inversus and sudden onset bronchiectasis with a sharp decline in respiratory function presenting later in life but without sinusitis or infertility.



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Madeeha Subhan, MBBS

Capital Hospital Islamabad, Ayub Teaching Hospital, Abbottabad

For correspondence:
madeehas99@gmail.com

Waleed Sadiq, M.D.

Department of Medicine, Shifa International Hospital

Madeeha Subhan, MBBS

Capital Hospital Islamabad, Ayub Teaching Hospital, Abbottabad

For correspondence:
madeehas99@gmail.com

Waleed Sadiq, M.D.

Department of Medicine, Shifa International Hospital