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Review article
peer-reviewed

Synchronous Uterine Metastases from Breast Cancer: Case Study and Literature Review



Abstract

Breast cancer rarely metastasizes to the uterus. Here, we report two breast cancer patients with synchronous metastases to the uterus. Case 1 highlights a 46-year-old female with invasive ductal carcinoma who presented with a breast mass and was found to have uterine enlargement on positron emission tomography (PET) scan. Biopsy revealed a metastatic 4 mm focus of breast cancer in the background of endometrial hyperplasia. Case 2 reports a 62-year-old postmenopausal female diagnosed with lobular carcinoma of the breast following an abnormal screening mammogram. A routine pap smear necessitated further workup, revealing simultaneous endometrial and cervical metastasis. Both patients did not have any gynecologic symptoms and presented a diagnostic challenge.



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Review article
peer-reviewed

Synchronous Uterine Metastases from Breast Cancer: Case Study and Literature Review


Author Information

Aisha Akhtar

Surgery, Texas Tech Health Sciences Center Lubbock

Atul Ratra Corresponding Author

TTUHSC, Texas Tech University Health Sciences Center

Yana Puckett

Department of Surgery, TTUHSC

Abu Baker Sheikh

Student, Texas Tech University Health Sciences Center

Catherine A. Ronaghan

Department of Surgery, Texas Tech University Health Sciences Center


Ethics Statement and Conflict of Interest Disclosures

Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.


Review article
peer-reviewed

Synchronous Uterine Metastases from Breast Cancer: Case Study and Literature Review


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Review article
peer-reviewed

Synchronous Uterine Metastases from Breast Cancer: Case Study and Literature Review

Aisha Akhtar">Aisha Akhtar, Atul Ratra">Atul Ratra , Yana Puckett">Yana Puckett, Abu Baker Sheikh">Abu Baker Sheikh, Catherine A. Ronaghan">Catherine A. Ronaghan

  • Author Information
    Aisha Akhtar

    Surgery, Texas Tech Health Sciences Center Lubbock

    Atul Ratra Corresponding Author

    TTUHSC, Texas Tech University Health Sciences Center

    Yana Puckett

    Department of Surgery, TTUHSC

    Abu Baker Sheikh

    Student, Texas Tech University Health Sciences Center

    Catherine A. Ronaghan

    Department of Surgery, Texas Tech University Health Sciences Center


    Ethics Statement and Conflict of Interest Disclosures

    Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

    Acknowledgements


    Article Information

    Published: November 13, 2017

    DOI

    10.7759/cureus.1840

    Cite this article as:

    Akhtar A, Ratra A, Puckett Y, et al. (November 13, 2017) Synchronous Uterine Metastases from Breast Cancer: Case Study and Literature Review. Cureus 9(11): e1840. doi:10.7759/cureus.1840

    Publication history

    Received by Cureus: July 12, 2017
    Peer review began: November 10, 2017
    Peer review concluded: November 10, 2017
    Published: November 13, 2017

    Copyright

    © Copyright 2017
    Akhtar et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 3.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

    License

    This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Breast cancer rarely metastasizes to the uterus. Here, we report two breast cancer patients with synchronous metastases to the uterus. Case 1 highlights a 46-year-old female with invasive ductal carcinoma who presented with a breast mass and was found to have uterine enlargement on positron emission tomography (PET) scan. Biopsy revealed a metastatic 4 mm focus of breast cancer in the background of endometrial hyperplasia. Case 2 reports a 62-year-old postmenopausal female diagnosed with lobular carcinoma of the breast following an abnormal screening mammogram. A routine pap smear necessitated further workup, revealing simultaneous endometrial and cervical metastasis. Both patients did not have any gynecologic symptoms and presented a diagnostic challenge.



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Aisha Akhtar

Surgery, Texas Tech Health Sciences Center Lubbock

Atul Ratra, M.D.

TTUHSC, Texas Tech University Health Sciences Center

For correspondence:
dratulratra@gmail.com

Yana Puckett

Department of Surgery, TTUHSC

Abu Baker Sheikh, M.D.

Student, Texas Tech University Health Sciences Center

Catherine A. Ronaghan

Department of Surgery, Texas Tech University Health Sciences Center

Aisha Akhtar

Surgery, Texas Tech Health Sciences Center Lubbock

Atul Ratra, M.D.

TTUHSC, Texas Tech University Health Sciences Center

For correspondence:
dratulratra@gmail.com

Yana Puckett

Department of Surgery, TTUHSC

Abu Baker Sheikh, M.D.

Student, Texas Tech University Health Sciences Center

Catherine A. Ronaghan

Department of Surgery, Texas Tech University Health Sciences Center