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Case report
peer-reviewed

Palliative Radiation Therapy for Symptom Control in an Advanced Case of Pseudomyxoma Peritonei



Abstract

Pseudomyxoma peritonei (PP) is a rare clinical condition characterized by progressive mucinous ascites, which is typically caused by a mucin-producing neoplasm. Reports of radiation therapy (RT) in the management of PP are limited. We report a unique case of a 62-year-old woman with severe, end-stage, recurrent PP and a large, mucin-secreting mass protruding through her abdominal wall. Low-dose, hypofractionated palliative RT was administered for symptom control with the hope of improving her quality of life. We suggest that radiation therapy be considered in the comprehensive palliative management of patients with PP.



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Case report
peer-reviewed

Palliative Radiation Therapy for Symptom Control in an Advanced Case of Pseudomyxoma Peritonei


Author Information

Clare McGrath

Faculty of Science, Biomedical Science, The University of Ottawa

Kelly Linden

Department of Radiation Medicine, The Ottawa Hospital Cancer Centre

Pamela Hube

Department of Radiation Medicine, The Ottawa Hospital Cancer Centre

Anna Adamiak

Department of Pathology and Laboratory Medicine, The Ottawa Hospital

Kristopher Dennis Corresponding Author

Division of Radiation Oncology, The University of Ottawa


Ethics Statement and Conflict of Interest Disclosures

Human subjects: Consent was obtained by all participants in this study. Conflicts of interest: The authors have declared that no conflicts of interest exist.

Acknowledgements

We are grateful for the support of the Arseneau-Henry Families Research Fund and the Joseph Doyle Research Fund.


Case report
peer-reviewed

Palliative Radiation Therapy for Symptom Control in an Advanced Case of Pseudomyxoma Peritonei


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Case report
peer-reviewed

Palliative Radiation Therapy for Symptom Control in an Advanced Case of Pseudomyxoma Peritonei

  • Author Information
    Clare McGrath

    Faculty of Science, Biomedical Science, The University of Ottawa

    Kelly Linden

    Department of Radiation Medicine, The Ottawa Hospital Cancer Centre

    Pamela Hube

    Department of Radiation Medicine, The Ottawa Hospital Cancer Centre

    Anna Adamiak

    Department of Pathology and Laboratory Medicine, The Ottawa Hospital

    Kristopher Dennis Corresponding Author

    Division of Radiation Oncology, The University of Ottawa


    Ethics Statement and Conflict of Interest Disclosures

    Human subjects: Consent was obtained by all participants in this study. Conflicts of interest: The authors have declared that no conflicts of interest exist.

    Acknowledgements

    We are grateful for the support of the Arseneau-Henry Families Research Fund and the Joseph Doyle Research Fund.


    Article Information

    Published: June 29, 2017

    DOI

    10.7759/cureus.1407

    Cite this article as:

    Mcgrath C, Linden K, Hube P, et al. (June 29, 2017) Palliative Radiation Therapy for Symptom Control in an Advanced Case of Pseudomyxoma Peritonei . Cureus 9(6): e1407. doi:10.7759/cureus.1407

    Publication history

    Received by Cureus: June 05, 2017
    Peer review began: June 12, 2017
    Peer review concluded: June 21, 2017
    Published: June 29, 2017

    Copyright

    © Copyright 2017
    McGrath et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 3.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

    License

    This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Pseudomyxoma peritonei (PP) is a rare clinical condition characterized by progressive mucinous ascites, which is typically caused by a mucin-producing neoplasm. Reports of radiation therapy (RT) in the management of PP are limited. We report a unique case of a 62-year-old woman with severe, end-stage, recurrent PP and a large, mucin-secreting mass protruding through her abdominal wall. Low-dose, hypofractionated palliative RT was administered for symptom control with the hope of improving her quality of life. We suggest that radiation therapy be considered in the comprehensive palliative management of patients with PP.



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Create a free account to continue reading this article.

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Clare McGrath, Co-op Student

Faculty of Science, Biomedical Science, The University of Ottawa

Kelly Linden

Department of Radiation Medicine, The Ottawa Hospital Cancer Centre

Pamela Hube

Department of Radiation Medicine, The Ottawa Hospital Cancer Centre

Anna Adamiak

Department of Pathology and Laboratory Medicine, The Ottawa Hospital

Kristopher Dennis

Division of Radiation Oncology, The University of Ottawa

For correspondence:
krdennis@toh.on.ca

Clare McGrath, Co-op Student

Faculty of Science, Biomedical Science, The University of Ottawa

Kelly Linden

Department of Radiation Medicine, The Ottawa Hospital Cancer Centre

Pamela Hube

Department of Radiation Medicine, The Ottawa Hospital Cancer Centre

Anna Adamiak

Department of Pathology and Laboratory Medicine, The Ottawa Hospital

Kristopher Dennis

Division of Radiation Oncology, The University of Ottawa

For correspondence:
krdennis@toh.on.ca