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Case report
peer-reviewed

Aripiprazole-Induced Neutropenia in a Seven Year-Old Male: A Case Report



Abstract

Blood dyscrasias are the widely known side effect of the second-generation antipsychotic medications. Aripiprazole rarely causes hematological side effects and it is considered relatively safe. We present the case report of a seven-year-old male who developed acute neutropenia a week after starting aripiprazole. His absolute neutrophil count (ANC) arose spontaneously once the medication was stopped. Clinicians should periodically check ANC in the patients taking aripiprazole as neutropenia could be lethal in extreme cases. To our knowledge, this is the first case report of leukopenia associated with aripiprazole in the child and adolescent population.



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Case report
peer-reviewed

Aripiprazole-Induced Neutropenia in a Seven Year-Old Male: A Case Report


Author Information

Muhammad Hassan Majeed

Department of Psychiatry, Quinnipiac University

Ali Ahsan Ali Corresponding Author

Brown University, Miriam Hospital


Ethics Statement and Conflict of Interest Disclosures

Human subjects: Consent was obtained by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.


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Case report
peer-reviewed

Aripiprazole-Induced Neutropenia in a Seven Year-Old Male: A Case Report

Muhammad Hassan Majeed">Muhammad Hassan Majeed, Ali Ahsan Ali">Ali Ahsan Ali

  • Author Information
    Muhammad Hassan Majeed

    Department of Psychiatry, Quinnipiac University

    Ali Ahsan Ali Corresponding Author

    Brown University, Miriam Hospital


    Ethics Statement and Conflict of Interest Disclosures

    Human subjects: Consent was obtained by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

    Acknowledgements


    Article Information

    Published: August 11, 2017

    DOI

    10.7759/cureus.1561

    Cite this article as:

    Majeed M, Ali A (August 11, 2017) Aripiprazole-Induced Neutropenia in a Seven Year-Old Male: A Case Report . Cureus 9(8): e1561. doi:10.7759/cureus.1561

    Publication history

    Received by Cureus: February 28, 2017
    Peer review began: June 05, 2017
    Peer review concluded: August 05, 2017
    Published: August 11, 2017

    Copyright

    © Copyright 2017
    Majeed et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 3.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

    License

    This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Blood dyscrasias are the widely known side effect of the second-generation antipsychotic medications. Aripiprazole rarely causes hematological side effects and it is considered relatively safe. We present the case report of a seven-year-old male who developed acute neutropenia a week after starting aripiprazole. His absolute neutrophil count (ANC) arose spontaneously once the medication was stopped. Clinicians should periodically check ANC in the patients taking aripiprazole as neutropenia could be lethal in extreme cases. To our knowledge, this is the first case report of leukopenia associated with aripiprazole in the child and adolescent population.



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Create a free account to continue reading this article.

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Muhammad Hassan Majeed

Department of Psychiatry, Quinnipiac University

Ali Ahsan Ali

Brown University, Miriam Hospital

For correspondence:
aliahsanloona@gmail.com

Muhammad Hassan Majeed

Department of Psychiatry, Quinnipiac University

Ali Ahsan Ali

Brown University, Miriam Hospital

For correspondence:
aliahsanloona@gmail.com