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Cost-Effectiveness of Cardiac Radiosurgery for Atrial Fibrillation: Implications for Reducing Health Care Morbidity, Utilization, and Costs



Abstract

In the United States (U.S.), atrial fibrillation (AF) is the second-most common cardiovascular condition after hypertension, affecting four million Americans each year. Individuals with AF are three times more likely to be hospitalized over the span of a year when compared to medically matched control groups. The considerably large clinical population of individuals with AF mandates that the cost-effectiveness and efficacy of current treatment regimens for AF have egregious implications for health care spending and public health. Unfortunately, catheter ablation for AF treatment has been shown to make only modest gains in quality-adjusted life years, has yet to demonstrate cost-utility advantages over conventional therapies for AF, and has a reported rate of recurrence for AF that is notably high. Thus, there is a major unmet clinical need for a therapeutic option to treat AF that produces more consistent and efficacious results that are cost-effective. Cardiac radiosurgery as a therapy for AF has the potential to be remarkably cost-effective and produce robust patient outcomes. CyberHeart Inc. has developed the world’s first-ever cardiac radiosurgery (CRS) system designed to ablate the heart non-invasively. Procedures that ablate the heart utilizing the Cyberheart CRS system are anticipated to allow higher efficacy and more consistent results than current techniques such as catheter ablation. The aim of this study is to present the current healthcare utilization and expenditures in AF treatment, report the cost-effectiveness of catheter ablation for AF, and project the potential cost-effectiveness of cardiac radiosurgery for the treatment of AF.



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Review article
peer-reviewed

Cost-Effectiveness of Cardiac Radiosurgery for Atrial Fibrillation: Implications for Reducing Health Care Morbidity, Utilization, and Costs


Author Information

Nikhilesh Bhatt Corresponding Author

Fogarty Institute for Innovation

Mintu Turakhia

Department of Cardiology, Stanford University School of Medicine

Thomas J. Fogarty

Fogarty Insitute for Innovation


Ethics Statement and Conflict of Interest Disclosures

Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: T. Fogarty serves on the board of CyberHeart Inc. .


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Investigational Cardiac Radiosurgery

Cost-Effectiveness of Cardiac Radiosurgery for Atrial Fibrillation: Implications for Reducing Health Care Morbidity, Utilization, and Costs

Nikhilesh Bhatt">Nikhilesh Bhatt , Mintu Turakhia">Mintu Turakhia, Thomas J. Fogarty">Thomas J. Fogarty

  • Author Information
    Nikhilesh Bhatt Corresponding Author

    Fogarty Institute for Innovation

    Mintu Turakhia

    Department of Cardiology, Stanford University School of Medicine

    Thomas J. Fogarty

    Fogarty Insitute for Innovation


    Ethics Statement and Conflict of Interest Disclosures

    Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: T. Fogarty serves on the board of CyberHeart Inc. .

    Acknowledgements


    Article Information

    Published: August 01, 2016

    DOI

    10.7759/cureus.720

    Cite this article as:

    Bhatt N, Turakhia M, Fogarty T J. (August 01, 2016) Cost-Effectiveness of Cardiac Radiosurgery for Atrial Fibrillation: Implications for Reducing Health Care Morbidity, Utilization, and Costs. Cureus 8(8): e720. doi:10.7759/cureus.720

    Publication history

    Received by Cureus: June 21, 2016
    Peer review began: June 26, 2016
    Peer review concluded: July 25, 2016
    Published: August 01, 2016

    Copyright

    © Copyright 2016
    Bhatt et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 3.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

    License

    This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

In the United States (U.S.), atrial fibrillation (AF) is the second-most common cardiovascular condition after hypertension, affecting four million Americans each year. Individuals with AF are three times more likely to be hospitalized over the span of a year when compared to medically matched control groups. The considerably large clinical population of individuals with AF mandates that the cost-effectiveness and efficacy of current treatment regimens for AF have egregious implications for health care spending and public health. Unfortunately, catheter ablation for AF treatment has been shown to make only modest gains in quality-adjusted life years, has yet to demonstrate cost-utility advantages over conventional therapies for AF, and has a reported rate of recurrence for AF that is notably high. Thus, there is a major unmet clinical need for a therapeutic option to treat AF that produces more consistent and efficacious results that are cost-effective. Cardiac radiosurgery as a therapy for AF has the potential to be remarkably cost-effective and produce robust patient outcomes. CyberHeart Inc. has developed the world’s first-ever cardiac radiosurgery (CRS) system designed to ablate the heart non-invasively. Procedures that ablate the heart utilizing the Cyberheart CRS system are anticipated to allow higher efficacy and more consistent results than current techniques such as catheter ablation. The aim of this study is to present the current healthcare utilization and expenditures in AF treatment, report the cost-effectiveness of catheter ablation for AF, and project the potential cost-effectiveness of cardiac radiosurgery for the treatment of AF.



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Nikhilesh Bhatt

Fogarty Institute for Innovation

For correspondence:
nbhatt@ucla.edu

Mintu Turakhia

Department of Cardiology, Stanford University School of Medicine

Thomas J. Fogarty, M.D.

Fogarty Insitute for Innovation

Nikhilesh Bhatt

Fogarty Institute for Innovation

For correspondence:
nbhatt@ucla.edu

Mintu Turakhia

Department of Cardiology, Stanford University School of Medicine

Thomas J. Fogarty, M.D.

Fogarty Insitute for Innovation