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Case report
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Unresectable Extraskeletal Myxoid Chondrosarcoma of the Neck: Early Tumor Response to Chemoradiotherapy



Abstract

Extraskeletal myxoid chondrosarcoma (EMC) rarely occurs in the head and neck and is generally managed with primary surgery. To our knowledge, no cases of unresectable EMC of the neck have been reported. We present a case of an unresectable EMC treated with chemotherapy and radiation, and highlight the exceptional early response to therapy. 



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Case report
peer-reviewed

Unresectable Extraskeletal Myxoid Chondrosarcoma of the Neck: Early Tumor Response to Chemoradiotherapy


Author Information

Mark Zaki Corresponding Author

Radiation Oncology, Detroit Medical Center

Department of Oncology, Division of Radiation Oncology, Karmanos Cancer Center

Department of Oncology, Division of Radiation Oncology, Wayne State University School of Medicine

Pam Laszewski

Radiation Oncology, Karmanos Cancer Center

Natasha Robinette

Diagnostic Radiology, Karmanos Cancer Center

Husain Saleh

Pathology, Detroit Medical Center

Naweed Raza

Otolaryngology, Karmanos Cancer Center

Ammar Sukari

Medical Oncology, Karmanos Cancer Center

Harold Kim

Radiation Oncology, Karmanos Cancer Center


Ethics Statement and Conflict of Interest Disclosures

Human subjects: Consent was obtained by all participants in this study. Conflicts of interest: The authors have declared that no conflicts of interest exist.


Case report
peer-reviewed

Unresectable Extraskeletal Myxoid Chondrosarcoma of the Neck: Early Tumor Response to Chemoradiotherapy


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Case report
peer-reviewed
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Exceptional Responders in Oncology

Unresectable Extraskeletal Myxoid Chondrosarcoma of the Neck: Early Tumor Response to Chemoradiotherapy

  • Author Information
    Mark Zaki Corresponding Author

    Radiation Oncology, Detroit Medical Center

    Department of Oncology, Division of Radiation Oncology, Karmanos Cancer Center

    Department of Oncology, Division of Radiation Oncology, Wayne State University School of Medicine

    Pam Laszewski

    Radiation Oncology, Karmanos Cancer Center

    Natasha Robinette

    Diagnostic Radiology, Karmanos Cancer Center

    Husain Saleh

    Pathology, Detroit Medical Center

    Naweed Raza

    Otolaryngology, Karmanos Cancer Center

    Ammar Sukari

    Medical Oncology, Karmanos Cancer Center

    Harold Kim

    Radiation Oncology, Karmanos Cancer Center


    Ethics Statement and Conflict of Interest Disclosures

    Human subjects: Consent was obtained by all participants in this study. Conflicts of interest: The authors have declared that no conflicts of interest exist.

    Acknowledgements


    Article Information

    Published: December 24, 2015

    DOI

    10.7759/cureus.432

    Cite this article as:

    Zaki M, Laszewski P, robinette N, et al. (December 24, 2015) Unresectable Extraskeletal Myxoid Chondrosarcoma of the Neck: Early Tumor Response to Chemoradiotherapy. Cureus 7(12): e432. doi:10.7759/cureus.432

    Publication history

    Received by Cureus: November 23, 2015
    Peer review began: November 25, 2015
    Peer review concluded: December 16, 2015
    Published: December 24, 2015

    Copyright

    © Copyright 2015
    Zaki et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 3.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

    License

    This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Extraskeletal myxoid chondrosarcoma (EMC) rarely occurs in the head and neck and is generally managed with primary surgery. To our knowledge, no cases of unresectable EMC of the neck have been reported. We present a case of an unresectable EMC treated with chemotherapy and radiation, and highlight the exceptional early response to therapy. 



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Create a free account to continue reading this article.

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Mark Zaki, M.D., Resident Physician

Radiation Oncology, Detroit Medical Center

For correspondence:
mazaki@med.wayne.edu

Pam Laszewski

Radiation Oncology, Karmanos Cancer Center

Natasha Robinette

Diagnostic Radiology, Karmanos Cancer Center

Husain Saleh

Pathology, Detroit Medical Center

Naweed Raza

Otolaryngology, Karmanos Cancer Center

Ammar Sukari

Medical Oncology, Karmanos Cancer Center

Harold Kim

Radiation Oncology, Karmanos Cancer Center

Mark Zaki, M.D., Resident Physician

Radiation Oncology, Detroit Medical Center

For correspondence:
mazaki@med.wayne.edu

Pam Laszewski

Radiation Oncology, Karmanos Cancer Center

Natasha Robinette

Diagnostic Radiology, Karmanos Cancer Center

Husain Saleh

Pathology, Detroit Medical Center

Naweed Raza

Otolaryngology, Karmanos Cancer Center

Ammar Sukari

Medical Oncology, Karmanos Cancer Center

Harold Kim

Radiation Oncology, Karmanos Cancer Center