"Never doubt that a small group of thoughtful, committed citizens can change the world. Indeed, it is the only thing that ever has."

Margaret Mead
Case report

Treatment of a Compression Fracture at a Previously Instrumented Lumbar Vertebral Body Using Balloon Kyphoplasty: A Technical Case Report


Compression fractures are common among osteoporotic patients and can be a significant source of pain and disability. Patients who suffer a compression fracture at an instrumented level of a lumbar fusion are most often treated conservatively. Herein, we demonstrate a safe and effective treatment for a vertebral compression fracture (VCF) at a previous level with instrumented fusion and pedicle screw fixation. An 89-year-old female with a history of multiple osteoporotic compression fractures treated with previous kyphoplasties and a prior instrumented fusion at L4-L5 presented with debilitating lower back pain for one week. After failing conservative management, computed tomography (CT) and magnetic resonance imaging (MRI) study of the lumbar spine revealed an acute VCF of the previously instrumented L5 vertebral body. Under biplanar fluoroscopy, a balloon kyphoplasty was performed at the L5 vertebrae utilizing the Inflatable Vertebral Augmentation System (IVAS) from Stryker® (Kalamazoo, MI, USA). We were able to demonstrate that the treatment of an acute VCF with balloon kyphoplasty is feasible in patients who have a history of previous instrumentation with pedicle screws remaining at the fracture level.


As many as 700,000 vertebral compression fractures (VCFs) occur each year in North America, with approximately one-fifth occurring in individuals over the age of 70 [1-2]. Posterior lumbar instrumented fusion is a common procedure in the treatment of degenerative spine disorders. Complications secondary to instrumented fusions include adjacent-segment breakdown, pseudarthrosis, as well as compression fractures [3-8]. However, few reports document treatment options for VCFs in previously instrumented segments [4-5,9] even though they are among the most common fractures of the spinal column due to osteoporosis [1,8]. These types of fractures not only cause debilitating pain, but can often result in disruption of activities of daily living as well as a significant decrease in quality of life [10-11]. Many patients respond favorably to conservative treatments such as bed rest, analgesics, and bracing [1,10]. However, there is evidence that minimally-invasive surgical options such as balloon kyphoplasty performed for patients without significant vertebral instability or neurological compromise can yield faster clinical improvement in pain and mobility, as well as restoration of vertebral body height [12] and a correction of sagittal imbalance [1,8,10,13]. We describe the kyphoplasty technique we used and its outcome on a patient with a previous L4-L5 instrumented fusion, who presented with an acute L5 compression fracture.

Case Presentation

An 89-year-old female presented with severe, worsening lower back pain for one week. She had a history of severe osteoporosis with previous kyphoplasties at T6, T7, T12, L2, and L4. Four years earlier, the patient underwent an L4-L5 instrumented fusion. An L4 kyphoplasty was performed at the time of the initial L4-L5 fusion. Upon evaluation, there was no neurological deficit. The patient could ambulate with a walker but was severely limited due to pain. Radiographic evaluation revealed a fracture involving the inferior endplate of L5 with associated edema on magnetic resonance imaging (MRI) and computed tomography (CT) (Figures 1-2). Her preoperative visual analogue scale (VAS) in regard to pain intensity was ranked between five to seven on a scale of ten with analgesic medication. After failing conservative treatment with analgesics, and demonstrating almost no tolerance for ambulation, the patient was offered a kyphoplasty and informed consent was obtained. Post-anesthesia care unit (PACU) evaluation after the procedure revealed almost complete resolution of lower back and leg pain. Postoperative VAS evaluation occurred on operative day and revealed a score of two out of ten. The patient was discharged to a subacute rehabilitation facility on the day after the kyphoplasty. On discharge, the patient ambulated with only minimal walker assistance. At a two-month postoperative evaluation, the patient demonstrated continual improvement in ambulation with near complete resolution of her lower back pain.

Surgical technique

The patient was positioned prone on a biplane table. Biplanar fluoroscopy was brought into the field and the targeted vertebral body was localized in both anterior-posterior (AP) and lateral projections. After infiltrating the skin and soft tissue with local anesthetic, a stab incision was made over the right pedicle. The kyphoplasty was performed using the Inflatable Vertebral Augmentation System (IVAS) developed by Stryker® (Kalamazoo, MI, USA). A Jamshidi needle was introduced from a transpedicular approach into the body of L5 via the right pedicle, inferior and lateral to the pedicle screw under biplanar fluoroscopic guidance. The osteo-introducer was then introduced into the vertebral body (Figures 3-4). This created the tract for the inflatable balloon. The balloon was then inserted and inflated to create a cavity within the vertebral body. After the balloon was removed, 5 milliliters of polymethylmethacrylate (PMMA) cement (high viscosity radiopaque bone cement, Stryker®) was infused into the vertebral body. There was no noted extravasation of cement beyond the border of the vertebral body. Once the cement had cured, the Jamshidi needle was removed. Final intraoperative X-rays were performed with fluoroscopy in both AP and lateral projections, confirming acceptable cement fixation without any significant breaching of any borders (Figures 5-6).


VCF can occur in up to 15% of patients who have undergone instrumented spinal fusion [14-16]. The mechanism is likely related to a decrease in bone mineral density and changing biomechanics that follow fusions [17]. This can be increasingly problematic, especially in aging populations. While VCF typically occurs in adjacent segments of previously fused levels, it can also occur in previously fused levels due to osteoporosis [14-16]. The latter presents a unique challenge for treatment, as transpedicular access to the vertebral body is compromised due to the presence of pedicle screws. These patients tend to get offered conservative treatment only and suffer from severe pain and associated morbidities due to prolonged bed rest and decreased activity. The recovery period with conservative treatment of analgesics, physical therapy, and bracing could last up to eight to twelve weeks [18]. This case demonstrates that despite the presence of pedicle screws, the vertebral body in the lumbar spine can still be accessed through careful fluoroscopic guidance using biplanar fluoroscopy. Most pedicles in the lumbar spine are between 8 and 15 millimeters in diameter, depending on the level, while most pedicle screws have an outer diameter of 5 to 7 millimeters [19]. This difference can still allow ample space to access the vertebral body. The screw itself can serve as a point of reference to guide the Jamshidi needle into the pedicle. Newer surgical instruments such as curved needles and directional Jamshidi needles facilitate better crossing of the midline using a uni-pedicular approach, which can accommodate unilateral treatment success and reduce the risk of compromising both pedicles. The outcome of this case demonstrates the described technique to be a safe and effective minimally invasive surgical alternative to conservative treatment. The kyphoplasty procedure in this patient led to an expedited recovery when compared to conservative treatment only.


This technical case report demonstrates that the treatment of acute lumbar VCF with balloon kyphoplasty is feasible even in the presence of pedicle screws at the affected vertebrae. Further randomized study will be needed to evaluate the superiority of this procedure over other treatment options.


  1. Yuan WH, Hsu HC, Lai KL: Vertebroplasty and balloon kyphoplasty versus conservative treatment for osteoporotic vertebral compression fractures: a meta-analysis. Medicine. 2016, 95:e4491. 10.1097/MD.0000000000004491
  2. McCarthy J, Davis A: Diagnosis and management of vertebral compression fractures. Am Fam Physician. 2016, 94:44-50.
  3. Boos N, Webb JK: Pedicle screw fixation in spinal disorders: a European view. Eur Spine J. 1997, 6:2-18. 10.1007/BF01676569
  4. Ha KY, Kwon SE, Kim KW, Oh IS, Lee YM: Vertebral compression fracture in the middle of fused segments without a history of injury: a case report. Spine. 2010, 35:E137-E139. 10.1097/BRS.0b013e3181b7ac6a
  5. Hart RA, Hiratzka J, Deodhar A: Case report: vertebral compression fracture in a fused and instrumented lumbar segment. Clin Orthop Relat Res. 2007, 458:226.
  6. Irwin ZN, Hilibrand A, Gustavel M, et al.: Variation in surgical decision making for degenerative spinal disorders. Part I: lumbar spine. Spine. 2005, 30:2208-2213. 10.1097/01.brs.0000181057.60012.08
  7. Kim SK, Chung JY, Seo HY, Lee WG: Vertebral compression fracture within a solid fusion mass without trauma after removal of pedicle screws. Spine J. 2016, 16:e219-e223. 10.1016/j.spinee.2015.11.053
  8. Wood KB, Li W, Lebl DS, Ploumis A: Management of thoracolumbar spine fractures. Spine J. 2014, 14:145-164. 10.1016/j.spinee.2012.10.041
  9. Pirris SM, Kimes SM: Compression fracture in the middle of a chronic instrumented fusion that developed into pseudarthrosis after balloon kyphoplasty. J Neurosurg Spine. 2014, 20:603-772. 10.3171/2014.2.SPINE13799
  10. Liang L, Chen X, Jiang W, Li X, Chen J, Wu L, Zhu Y: Balloon kyphoplasty or percutaneous vertebroplasty for osteoporotic vertebral compression fracture? An updated systematic review and meta-analysis. Ann Saudi Med. 2016, 36:165-174. 10.5144/0256-4947.2016.165
  11. Silverman SL: The clinical consequences of vertebral compression fracture. Bone. 1992, 13:S27-S31. 10.1016/8756-3282(92)90193-Z
  12. Lieberman IH, Dudeney S, Reinhardt MK, Bell G: Initial outcome and efficacy of “kyphoplasty” in the treatment of painful osteoporotic vertebral compression fractures. Spine. 2001, 26:1631.
  13. Klazen CA, Lohle PN, de Vries J, et al.: Vertebroplasty versus conservative treatment in acute osteoporotic vertebral compression fractures (Vertos II): an open-label randomised trial. The Lancet. 2010, 376:1085-1092. 10.1016/S0140-6736(10)60954-3
  14. Li YC, Yang SC, Chen HS, Kao YH, Tu YK: Impact of lumbar instrumented circumferential fusion on the development of adjacent vertebral compression fracture. Bone Joint J. 2015, 97:1411-1416. 10.1302/0301-620X.97B10.34927
  15. Pacione D, Kim I, Wilson TA, Frempong-Boadu A: Cortical screw trajectory for instrumentation and fusion in the setting of osteopathic compression fracture allows for percutaneous kyphoplasty for adjacent level compression fractures. J Clin Neurosci. 2015, 22:899-904. 10.1016/j.jocn.2014.09.025
  16. Toyone T, Ozawa T, Kamikawa K, et al.: Subsequent vertebral fractures following spinal fusion surgery for degenerative lumbar disease: a mean ten-year follow-up. Spine. 2010, 35:1915. 10.1097/BRS.0b013e3181dc846c
  17. Bogdanffy GM, Ohnmeiss DD, Guyer RD: Early changes in bone mineral density above a combined anteroposterior L4-S1 lumbar spinal fusion: a clinical investigation. Spine. 1995, 20:1674-1678.
  18. Rousing R, Andersen MO, Jespersen SM, Thomsen K, Lauritsen J: Percutaneous vertebroplasty compared to conservative treatment in patients with painful acute or subacute osteoporotic vertebral fractures: three-months follow-up in a clinical randomized study. Spine. 2009, 34:1349. 10.1097/BRS.0b013e3181a4e628
  19. Bernard JT, Seibert CE: Pedicle diameter determined by computed tomography: its relevance to pedicle screw fixation in the lumbar spine. Spine. 1992, 17:S160-S163.
Case report

Treatment of a Compression Fracture at a Previously Instrumented Lumbar Vertebral Body Using Balloon Kyphoplasty: A Technical Case Report

Author Information

Chad Claus Corresponding Author

Neurosurgery, Ascension Providence Hospital, Michigan State University, College of Human Medicine, Southfield, USA

Evan Lytle

Neurosurgery, Ascension Providence Hospital, Michigan State University, College of Human Medicine, Southfield, USA

Lucas Garmo

Neurosurgery, Ascension Providence Hospital, Michigan State University, College of Human Medicine, Southfield, USA

Doris Tong

Neurosurgery, Ascension Providence Hospital, Michigan State University, College of Human Medicine, Southfield, USA

Boyd Richards

Neurosurgery, Ascension Providence Hospital, Michigan State University, College of Human Medicine, Southfield, USA

Ethics Statement and Conflict of Interest Disclosures

Human subjects: Consent was obtained by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Case report

Treatment of a Compression Fracture at a Previously Instrumented Lumbar Vertebral Body Using Balloon Kyphoplasty: A Technical Case Report

Figures etc.


Scholary Impact Quotient™ (SIQ™) is our unique post-publication peer review rating process. Learn more here.