The Effect of Dietary Lutein, Folate, and B-Vitamin on Cataract Progression in the Age-Related Eye Disease Study (AREDS)


Abstract

PURPOSE: To determine nutritional intake effects on cataract incidence and progression. METHODS: 4757 persons (55-80 years) were assessed with lens photographs and a food frequency questionnaire, divided into nutrient intake quintiles (Q1-5), and followed for 10 years. We used multivariate logistic regression models. RESULTS: For Q5 vs. Q1 (p < 0.05), increased lutein consumption correlated with decreased cortical cataracts (OR 0.68). Nuclear cataracts decreased with increased intake of vitamins B2 (OR 0.59), B6 (OR 0.64), and B12 (OR 0.66). No associations were seen for vitamins B1, B3, and folate. CONCLUSION: Increased dietary intake of vitamins B2, B6, B12, and lutein was associated with decreased incidence of cataract development or progression.
Poster
non-peer-reviewed

The Effect of Dietary Lutein, Folate, and B-Vitamin on Cataract Progression in the Age-Related Eye Disease Study (AREDS)


Author Information

Grace Shih Corresponding Author

Vanderbilt University


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