Abstract

Linear IgA bullous dermatosis (LABD) is a rare autoimmune blistering disorder characterized by linear deposition of IgA at the dermo-epidermal junction. In pediatric patients, LABD can mimic other autoimmune and infectious skin conditions, complicating diagnosis and delaying treatment. We present the case of a 14-month-old male with disseminated bullous lesions initially misdiagnosed as non-bullous impetigo with MRSA. The diagnosis was confirmed through direct immunofluorescence (DIF), which revealed linear IgA deposition with neutrophil predominance. Treatment with dapsone led to significant improvement within one week, despite the complication of asymptomatic microcytic anemia, managed with iron supplementation and close monitoring. This case underscores the importance of DIF in distinguishing LABD from similar conditions and highlights the efficacy and safety of dapsone therapy with appropriate monitoring in infants. Clinicians should remain vigilant for potential side effects and recurrences, ensuring long-term follow-up and comprehensive management.