Abstract
Drug-induced liver injury (DILI) accounts for 50% of all acute hepatitis patients. Many medications can cause DILI; however, anti-tuberculosis medications are well-known causes, particularly isoniazid. Isoniazid hepatitis can present as asymptomatic transaminitis or as a classic presentation of liver dysfunction, such as jaundice, nausea, vomiting, and abdominal pain. Current research suggests that N-acetylcysteine (NAC) via IV administration treatment is associated with positive outcomes, with fewer patients progressing to acute liver failure. Our patient's response to NAC treatment supports current clinical use.
