Abstract
Epidermodysplasia verruciformis is an autosomal recessive genetic skin disorder that results in an impaired immune response and increased susceptibility to certain types of HPV. The lesions present in early childhood and are polymorphic in appearance, with flat-topped, wart-like papules and both hyper and hypopigmented macules. A tissue biopsy is recommended for a definitive diagnosis.
No definitive treatment exists for EV. Lesions have a high likelihood of progression to squamous cell carcinoma; therefore, mainstays of treatment include frequent monitoring and sun protective measures.
