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Case report
peer-reviewed

A Case of Radiation Recall Dermatitis of Scalp in Acute Lymphoblastic Leukemia After Prophylactic Cranial Radiotherapy



Abstract

The radiation recall dermatitis (RRD) phenomenon is defined as the “recalling” of the skin following the administration of drugs; this induces a response or flare-like reaction over the skin that is exposed to radiation. In this case report, a young female developed RRD on Day 18 after the completion of cranial radiotherapy, that is, four days after the restart of the chemotherapy with doxorubicin. It is a self-limiting condition with supportive care as the treatment. When encountered in hematological malignancies, undue treatment breaks can delay definitive treatment and can eventually cause a relapse. 



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Case report
peer-reviewed

A Case of Radiation Recall Dermatitis of Scalp in Acute Lymphoblastic Leukemia After Prophylactic Cranial Radiotherapy


Author Information

Ponraj Madasamy

Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

Jogamaya Pattnaik

Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

Murali Paramanandhan Corresponding Author

Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

Biswajit Dubashi

Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

Naresh Jadhav

Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

Jagdeep Singh

Department of Medical Oncology, RCC, Jipmer, Pondicherry, India


Ethics Statement and Conflict of Interest Disclosures

Human subjects: Consent was obtained by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Acknowledgements

The authors thank Dr. Smita Kayal for her support and motivation in bringing about this article. Also, they express gratitude to the postgraduate (PG) students of the department: Dr. Kiran, Dr. Esha, and Dr. Bhanu Prakash.


Case report
peer-reviewed

A Case of Radiation Recall Dermatitis of Scalp in Acute Lymphoblastic Leukemia After Prophylactic Cranial Radiotherapy


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Case report
peer-reviewed

A Case of Radiation Recall Dermatitis of Scalp in Acute Lymphoblastic Leukemia After Prophylactic Cranial Radiotherapy

Ponraj Madasamy">Ponraj Madasamy, Jogamaya Pattnaik">Jogamaya Pattnaik, Murali Paramanandhan">Murali Paramanandhan , Biswajit Dubashi">Biswajit Dubashi, Naresh Jadhav">Naresh Jadhav, Jagdeep Singh">Jagdeep Singh

  • Author Information
    Ponraj Madasamy

    Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

    Jogamaya Pattnaik

    Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

    Murali Paramanandhan Corresponding Author

    Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

    Biswajit Dubashi

    Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

    Naresh Jadhav

    Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

    Jagdeep Singh

    Department of Medical Oncology, RCC, Jipmer, Pondicherry, India


    Ethics Statement and Conflict of Interest Disclosures

    Human subjects: Consent was obtained by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

    Acknowledgements

    The authors thank Dr. Smita Kayal for her support and motivation in bringing about this article. Also, they express gratitude to the postgraduate (PG) students of the department: Dr. Kiran, Dr. Esha, and Dr. Bhanu Prakash.


    Article Information

    Published: September 10, 2017

    DOI

    10.7759/cureus.1671

    Cite this article as:

    Madasamy P, Pattnaik J, Paramanandhan M, et al. (September 10, 2017) A Case of Radiation Recall Dermatitis of Scalp in Acute Lymphoblastic Leukemia After Prophylactic Cranial Radiotherapy. Cureus 9(9): e1671. doi:10.7759/cureus.1671

    Publication history

    Received by Cureus: July 25, 2017
    Peer review began: August 24, 2017
    Peer review concluded: September 07, 2017
    Published: September 10, 2017

    Copyright

    © Copyright 2017
    Madasamy et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 3.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

    License

    This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

The radiation recall dermatitis (RRD) phenomenon is defined as the “recalling” of the skin following the administration of drugs; this induces a response or flare-like reaction over the skin that is exposed to radiation. In this case report, a young female developed RRD on Day 18 after the completion of cranial radiotherapy, that is, four days after the restart of the chemotherapy with doxorubicin. It is a self-limiting condition with supportive care as the treatment. When encountered in hematological malignancies, undue treatment breaks can delay definitive treatment and can eventually cause a relapse. 



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Create a free account to continue reading this article.

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Ponraj Madasamy

Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

Jogamaya Pattnaik

Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

Murali Paramanandhan, M.D.

Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

For correspondence:
josh.messi19@gmail.com

Biswajit Dubashi

Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

Naresh Jadhav

Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

Jagdeep Singh

Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

Ponraj Madasamy

Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

Jogamaya Pattnaik

Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

Murali Paramanandhan, M.D.

Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

For correspondence:
josh.messi19@gmail.com

Biswajit Dubashi

Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

Naresh Jadhav

Department of Medical Oncology, RCC, Jipmer, Pondicherry, India

Jagdeep Singh

Department of Medical Oncology, RCC, Jipmer, Pondicherry, India