A Single Center Experience of Phase-gated Lung Stereotactic Ablative Radiotherapy



Abstract

Objectives:

A retrospective review of SABR lung patients was conducted to audit the use of phase-gated lung SABR at our centre.

Methods:

For patients who cannot achieve a reliable breath-hold technique, institutional policy mandates a motion management strategy when motion of GTV on 4DCT exceeds 5mm in any direction. For patients with < 5mm motion an ITV method is used with GTV contoured on all phases of the respiratory cycle to create a respiratory GTV denoted iGTV. If >5mm GTV motion exists in any direction a phase-gated approach is adopted with the gating window restricted to phases around end-expiration with < 5mm motion. A phase-gated GTV is contoured on each phase of the gating window to create an iGTV eg iGTV30-70. For mobile tumours a phase-gated approach reduces the PTV compared to the ITV method and may result in reduced risk of toxicity.

Results:

In our centre, 22 patients with either primary or metastatic lung cancer were treated between 2020 and 2022 using phase-gated lung SABR. The majority of these patients were treated using 2 VMAT FFF half-arcs, with only 2 patients requiring a 3-arc plan.

Conclusion(s):

A phase-gated approach provides an attractive method of reduction in the volume of the PTV.

A gated 4D-CBCT demonstrates a ‘like-for-like’ dataset, providing clarity in relation to online image review and reducing possibilities of mismatch, particularly in the longitudinal plane where mismatches can occur using the ITV method and standard CBCT.

Phase-gated lung SABR typically results in longer treatment sessions compared with free-breathing delivery.

Related content

abstract
non-peer-reviewed

A Single Center Experience of Phase-gated Lung Stereotactic Ablative Radiotherapy


Author Information

Laura Barry Corresponding Author

Radiotherapy, Bon Secours Radiotherapy Cork in Partnership with UPMC Hillman Cancer Centre, Cork, IRL

Paul J. Kelly

Radiotherapy, Bon Secours Radiotherapy Cork in Partnership with UPMC Hillman Cancer Centre, Cork, IRL

Erica Bennett

Radiotherapy, Bon Secours Radiotherapy Cork in Partnership with UPMC Hillman Cancer Centre, Cork, IRL


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