Overall Survival and Local Control of Hepatic Metastatic Lesions Treated with Stereotactic Body Radiotherapy



Abstract

Objectives:

Determine the local control (LC) and overall survival (OS) rate in patients treated with hepatic stereotactic bodey radiotherapy (SBRT) from 2017 to 2022

Methods:

A retrospective review was performed from January 2017 to August 2022 of the 68 SBRT cases identified. Eleven patients were included in the analysis with: 1-5 metastases, unresectable, maximum diameter of 6 cm in single lesion or ≤10 cm in combination, oligometastatic or oligoprogressive disease, adequate liver function (Child Pugh A-B), life expectancy > 6 months and KPS 80-100.

Results:

11 patients with 19 hepatic metastases were included, with an average age of 66 years old. Median follow-up was 13 months. The mean number of lesions per patient was 2 with a mean PTV of 45.5cc. The most commonly used scheme was 50 Gy in 5 sessions of 10 Gy each, with a median BED of 87.3 Gy. OS at 1 and 2 years was 75%. LC at 1 and 2 years was 83% and 42%, respectively.

Conclusion(s):

The study confirms that SBRT in liver metastases is a safe and effective treatment with high control rates higher than 80% at one year with SBRT, so we believe it should be promoted in our environment in properly selected patients and with centers that have the technology to perform it.

Related content

abstract
non-peer-reviewed

Overall Survival and Local Control of Hepatic Metastatic Lesions Treated with Stereotactic Body Radiotherapy


Author Information

Crhys E. Figon Muñoz Corresponding Author

Radiotherapy, UMAE 25, Monterrey, MEX

Francisco Lozano

Radiation Oncology, Medica Sur, Mexico City, MEX

M Adela Poitevin Chacón

Radiotherapy, Medica Sur, Mexico City, MEX


PDF Share