I am Dr. Abdulaziz Saleh Bamahel, a Master’s student in Biochemistry and Molecular Biology at Jiamusi University. My research focuses on the molecular mechanisms of inflammation and tissue degeneration, particularly in the context of osteoarthritis (OA). I am currently studying the role of macrophage polarization and metabolic reprogramming in OA progression, using both wild-type and myeloid cell-depleted C57BL/6J mice models. My work involves advanced histological, molecular, and immunological techniques such as qRT-PCR, immunohistochemistry (IHC), immunofluorescence (IF), and co-culture assays.

In parallel, I have authored a comprehensive review on the therapeutic role of microRNA-122-5p in hypoxic-ischemic brain injury (HIE), exploring gene regulation pathways involving PTEN, PDK1, and caspase-mediated apoptosis.

I am passionate about translational research bridging basic molecular insights with therapeutic potential, especially in the areas of neuroinflammation, cartilage regeneration, and microRNA-based treatments. I actively participate in academic peer reviewing and aim to contribute to the scientific community through both research and collaborative publications.

ORCID ID

http://orcid.org/0009-0006-4331-241X