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Psychiatric disorders in Prader-Willi syndrome: a case report about psychotic symptoms


Abstract

Background: Psychiatric symptoms are prevalent in patients with Prader-Willi syndrome (PWS), mainly behaviour disorders (temper tantrums and stubbornness) and manipulative behaviour, obsessive-compulsive characteristics in relation with food. True psychosis is evident in young adulthood in approximately 5-10% of patients. 
Aim & Objectives: review of psychotic symptoms in patients with a diagnosis of PWS to purpose of a case.
Methods/Study Design: a PWS case report with psychotic symptoms treated with Aripiprazole.
Results/Findings: PWS patients have an increased risk of psychotic disorder or affective illness with a psychotic component, especially young adult patients and those with the maternal uniparental disomy as opposed to paternal deletion. 
Conclusion: Behavioural and psychiatric problems interfere the most with quality of life in adulthood. These should be detected early and treated appropriately with parental education and psychotropic medication if it was necessary. Serotonin agonists have been the most successful in reducing temper outbursts and improving compulsivity. Psychosis is treated in a standard manner.
 

Poster
non-peer-reviewed

Psychiatric disorders in Prader-Willi syndrome: a case report about psychotic symptoms


Author Information

Marta Herrera Durán Corresponding Author

Mental Health, Hospital Clínico Universitario Virgen de la Victoria

Carlos ´Gómez Sánchez-Lafuente

Mental Health, Hospital Clínico Universitario, Málaga

Rocío Reina Gónzalez

General Medicine, Hospital General Universitario Carlos Haya, Málaga


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  • Author Information
    Marta Herrera Durán Corresponding Author

    Mental Health, Hospital Clínico Universitario Virgen de la Victoria

    Carlos ´Gómez Sánchez-Lafuente

    Mental Health, Hospital Clínico Universitario, Málaga

    Rocío Reina Gónzalez

    General Medicine, Hospital General Universitario Carlos Haya, Málaga

    Poster Information
    Meeting

    First International Online BioMedical Conference September 09, 2015 - September 12, 2015

    Publication history

    Received by Cureus: August 28, 2015
    Published: September 09, 2015

    License

    This is an open access poster distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: Psychiatric symptoms are prevalent in patients with Prader-Willi syndrome (PWS), mainly behaviour disorders (temper tantrums and stubbornness) and manipulative behaviour, obsessive-compulsive characteristics in relation with food. True psychosis is evident in young adulthood in approximately 5-10% of patients. 
Aim & Objectives: review of psychotic symptoms in patients with a diagnosis of PWS to purpose of a case.
Methods/Study Design: a PWS case report with psychotic symptoms treated with Aripiprazole.
Results/Findings: PWS patients have an increased risk of psychotic disorder or affective illness with a psychotic component, especially young adult patients and those with the maternal uniparental disomy as opposed to paternal deletion. 
Conclusion: Behavioural and psychiatric problems interfere the most with quality of life in adulthood. These should be detected early and treated appropriately with parental education and psychotropic medication if it was necessary. Serotonin agonists have been the most successful in reducing temper outbursts and improving compulsivity. Psychosis is treated in a standard manner.
 

Marta Herrera Durán

Mental Health, Hospital Clínico Universitario Virgen de la Victoria

For correspondence:
herreraduran@hotmail.com

Carlos ´Gómez Sánchez-Lafuente

Mental Health, Hospital Clínico Universitario, Málaga

Rocío Reina Gónzalez

General Medicine, Hospital General Universitario Carlos Haya, Málaga

Marta Herrera Durán

Mental Health, Hospital Clínico Universitario Virgen de la Victoria

For correspondence:
herreraduran@hotmail.com

Carlos ´Gómez Sánchez-Lafuente

Mental Health, Hospital Clínico Universitario, Málaga

Rocío Reina Gónzalez

General Medicine, Hospital General Universitario Carlos Haya, Málaga

Marta Herrera Durán

Mental Health, Hospital Clínico Universitario Virgen de la Victoria

For correspondence:
herreraduran@hotmail.com

Carlos ´Gómez Sánchez-Lafuente

Mental Health, Hospital Clínico Universitario, Málaga

Rocío Reina Gónzalez

General Medicine, Hospital General Universitario Carlos Haya, Málaga

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