Case Report
Amantadine-induced livedo reticularis - Case report*
Maria Victória Quaresma, Ana Carolina Dias Gomes, Aline Serruya, Dâmia Leal Vendramini, Lara Braga, Alice Mota Buçard
Published:
DOI:
10.1590/abd1806-4841.20153394
License:
© 2015 by Anais Brasileiros de DermatologiaThis is an Open Access article distributed under the terms of the Creative
Commons Attribution Non-Commercial License which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the
original work is properly cited.
Abstract
Livedo reticularis is a spastic-anatomical condition of the small vessels which translates morphologically by a reticular pattern, interspersing cyanosis, pallor and erythema. The same can be congenital or acquired. Among the acquired, we highlight the physiological livedo reticularis and the idiopathic livedo by vasospasm; the latter configures the most common cause. The drug-induced type is less common. The drugs amantadine and norepinephrine are often implicated. Cyanosis is usually reversible if the causative factor is removed, however, with chronicity, the vessels may become permanently dilated and telangiectatic. We report a case of a patient diagnosed with Parkinson’s disease with chronic livedo reticularis associated with the use of amantadine and improvement after discontinuation of the drug.