Research Article
Successes and pitfalls of chronic peritoneal dialysis in infants – a Polish nationwide outcome study
Anna Jander, Irena Makulska, Joanna Latoszyńska, Hanna Boguszewska-Bączkowska, Irena Bałasz-Chmielewska, Ilona Zagożdżon, Iga Załuska-Leśniewska, Ewa Stefaniak, Beata Leszczyńska, Katarzyna Zachwieja, Ryszard Wierciński, Hanna Kipigroch, Barbara Kołłątaj, Marcin Tkaczyk
Published:
June 30, 2010
DOI:
10.5114/aoms.2010.14265
License:
Copyright © 2010 Termedia & Banach2010This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
IntroductionPeritoneal dialysis (PD) is a preferred method of renal replacement therapy for end-stage renal disease in children. Recent advances have allowed chronic PD to be provided to children of all ages and sizes.Material and methodsThe study was designed as a national (10 dialysis centres), multicentre retrospective analysis of the medical history of 33 children who started chronic peritoneal dialysis in their infancy between 1993 and 2005, with a follow-up period of at least 24 months.ResultsThe nutritional status of the infants was unsatisfactory. The mean SDS of body weight at the start was –2.0, at 1 year of age –1.7. Only 40% of infants were adequately nourished at 1 year of age. Long-term follow-up analysis showed that 12 children received a kidney transplant, 13 were still on dialysis (4 changed method) and 6 died (mortality rate in the first year of life of 9%). In 2 children we observed an improvement of renal function. We observed a relatively high (1/8.8 patient-months) peritonitis rate in the analysed children when compared to 1 : 22 patient-months in all children undergoing PD in Poland.ConclusionsThe results of our survey have shown that the management of dialysed infants is still a challenge for the medical team and families, but long-term results of the therapy are encouraging.