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Case Report

Detection of a PDGFRB fusion in refractory CMML without eosinophilia: A case for broad spectrum tumor profiling



Abstract

In this case report, we describe a refractory CMML case without eosinophilia harboring a PDGFRB rearrangement leading to a favorable response with imatinib. We believe this case demonstrates the utility of broad spectrum genomic profiling in refractory CMML cases as an opportunity to uncover additional treatment options.


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