Access to Family Planning Services Following Natural Disasters and Pandemics: A Review of the English Literature

Background: When natural disasters strike, there is a sudden decrease in access to care due to infrastructure loss and displacement. A pandemic has the similar ability to acutely limit access to care. The relationship between decreased access to care and natural disasters has been previously explored. Objective: The purpose of this article is to present a focused review of the available and emerging literature regarding the overall impact of natural disasters and pandemics on unintended pregnancy and decreased care in this setting. Methods: A literature search was conducted on PubMed, Cochrane, Google Scholar, and Embase databases. The search was restricted to studies that were population-based, prospective or retrospective. Only peer-reviewed articles were considered. The search was further restricted to manuscripts in English or officially translated manuscripts. All qualifying papers from which data were extracted were subjected to a quality assessment conducted by two independent investigators (SK and AA). Each investigator reviewed all nine papers relevant to data collection using the Effective Public Health Practice Project (EPHP). MeSH terms were utilized across various databases. Studies were selected that were population-based, prospective or retrospective. Case reports and case series were not used. The primary outcomes were the rates of unintended pregnancy. Secondary outcomes included the use of contraception, short interval pregnancy, and access to reproductive services. Results: An initial search yielded 74 papers, of which nine papers were reviewed for qualitative data, examining the subjects affected by natural disasters or pandemics. An additional two papers regarding theoretical data and COVID-19 were analyzed. Although there seems to be a rise in unintended pregnancy and more difficulty accessing care following natural disasters and pandemics, there are variations in the rates based on region and event. Conclusions: The full effects of the COVID-19 pandemic on the rates of unplanned pregnancies will become apparent in the months and years to come. As obstetrician-gynecologists, we must communicate openly with our patients regarding the use of available contraception, sexual education, and family planning services at times of natural disasters and pandemics.


Introduction And Background Introduction
Between the years 2015 and 2019, it is estimated that each year 121 million pregnancies globally were unintended [1]. This reflects a global unintended pregnancy rate of 64 per 1,000 women of reproductive age [1]. The Centers for Disease Control and Prevention (CDC) notes that unintended pregnancy is one that is "either unwanted, such as that which occurred when no children or no more children were desired, or a pregnancy that is mistimed, such as a pregnancy that occurred earlier than desired." [2] Attempts to decrease unintended pregnancy focus on increasing access to family planning and contraceptive services as it is believed that these services are vital to providing patients of reproductive age with the necessary contraceptive care, screenings, and tests to make informed health choices regarding pregnancy [3]. The Guttmacher Institute has estimated that in 2016, two million pregnancies were postponed or avoided by the use of contraception prescribed by providers [4]. It is also estimated that these pregnancies could have resulted in approximately one million births and nearly 700,000 abortions [4].
Pandemics and natural disasters have both been shown to decrease the access to family planning services either by the destruction of healthcare facilities and infrastructure or by reduced capacity for care due to social distancing, clinic closures, travel restrictions, or economic slowdowns [5]. Initial findings show that contraceptive supply chains and family planning services have already been disrupted and negatively impacted by COVID-19 [5]. With one in six patients reporting increased difficulty in accessing contraception during the current pandemic [6], it is imperative that providers find a way to meet the demand for family planning services to ensure the health and safety of their patients and prevent unintended pregnancy.

Objectives
When natural disasters occur, there is a sudden decrease in access to care due to infrastructure loss and displacement. A pandemic has a similar ability to limit access to care [5]. The relationship between decreased access to care and natural disasters has been previously explored. The purpose of this article is to present a focused review of the available and emerging literature on the overall impact of natural disasters and pandemics on unintended pregnancy based on patient cohorts pre-and post-exposure. Theoretical data related to the current COVID-19 pandemic and the impact and overall risk of decreased care in this setting are also utilized.

Search Strategy
The following electronic search engines were used to find manuscripts regarding unplanned pregnancy during natural disasters and pandemics: PubMed, Google Scholar, Cochrane, and Embase database. Keyword MeSH terms utilized for the search included "unintended pregnancy," "unplanned pregnancy," "natural disasters," "hurricanes," "earthquakes," "floods," "COVID-19," "epidemics," and "pandemics." This search yielded 74 manuscripts between two investigators (AA and SK). Duplicates were removed, and 61 manuscripts remained. A manual assessment of the references in these 61 manuscripts was performed to further broaden the search and improve accuracy. Additional manuscripts were not identified from this assessment, and the final literature search yielded 61 manuscripts, all of which were screened using eligibility criteria. Of the 61 manuscripts, 11 manuscripts met inclusion criteria and were analyzed. Nine of the 11 manuscripts contained non-theoretical data, while the remaining two manuscripts contained theoretical data regarding the COVID-19 pandemic (Figure 1).

Study Selection and Eligibility Criteria
Manuscripts describing unplanned pregnancy in relation to natural disasters or pandemics were considered eligible for analysis. The search was restricted to studies that were population-based, prospective or retrospective. Only peer-reviewed articles or those published in peer-reviewed journals were considered. The search was further restricted to manuscripts in English or officially translated manuscripts. The exclusion criteria included case reports, case studies, qualitative assessments, and opinion pieces. This review paper was exempt from institutional review board approval.

Study Quality Assessment
All qualifying papers were also subjected to a quality assessment conducted by two independent investigators (SK and AA). Each investigator assessed all nine non-theoretical papers using the Effective Public Health Practice Project (EPHP) [7]. Each paper was assigned a "grade" using a 1-3 system with 1 being "strong" and 3 being "weak" based on factors such as selection bias, study design, confounding variables, dropouts, method of blinding, and withdrawals. A "final quality grade" was assigned to each paper, and the two independent investigators (SK and AA) compared the final quality grade assigned to each paper. Final quality grades were included in Table 1. A third blind reviewer was available for any disagreements between the reviewers; however, there were no discrepancies between the reviewers regarding final quality grades.

Outcomes Assessed in Literature Review
The primary outcomes were the rates of unintended pregnancy. These values were extracted from papers that collected data via self-report from patients and theoretical data projecting the effects of decreased access to care during the COVID-19 pandemic. Other outcomes included difficulty accessing reproductive health services, the use of birth control overall, new use of intrauterine devices (IUDs), new use of oral contraceptives, the desire to become pregnant, and frequency of sexual intercourse. The adverse effects studied were neonatal morbidity, short interpregnancy interval, vaginal infections/vaginal discharge/odor, and menstrual disorders.
The predictions for the COVID-19 pandemic summarized were derived from recent data from two studies utilizing a predictive mathematical model that estimated outcomes based on either a three-or 12-month family planning service disruptions, a 10% decline in family planning services overall, or a 10% shift in abortion care from safe to unsafe abortions [5,16].

Characteristics of Selected Studies
Nine studies met inclusion criteria and are described in Table 1. Four studies described earthquakes, two described hurricanes, and three described current COVID-19 data. There were eight cohort studies and one cross-sectional study. Two additional papers described theoretical COVID-19 predictions.

Unintended Pregnancy
Unintended pregnancy in those exposed to the COVID-19 pandemic or natural disasters was assessed. Data relating unintended pregnancy to exposure to natural disasters was specifically found in relation to Hurricane Katrina in the United States in 2005, the 2003 earthquake in Bam city, Iran, and the 2010 earthquake in Haiti. Studies have shown the rates of unintended pregnancy within subsets of the population in these countries to be 47% in the United States in 2019 [17], 27% in Iran in 2019 [18], and 61.2% in Haiti in 2018 [19].
In the aftermath of Hurricane Katrina, one study reported that 4% of their 55-person cohort experienced an unintended pregnancy because of loss of care secondary to the Hurricane Katrina displacement (p = 0.25) [8]. Similarly, in Bam city, Iran, a study found that 28.1% of the 256 pregnancies assessed were considered to be unintended in the province prior to the natural disaster compared to a previous baseline of 18.6% of unintended pregnancies [9]. A study of the effects of the 2010 Haitian earthquake found that births occurring post-earthquake were less likely to be wanted compared to births prior to the 2010 disaster [10].
One study regarding COVID-19 found 15 (14.9%) unintended pregnancies in a cohort of 101 noncohabitation/single subjects in Catania, Italy [6]. The incidence of unintended pregnancy in Italy was noted to be 28 per 1,000 women aged 15-49 between 2015 and 2019 [20]. Incidence within the Catania community specifically is not available. In northwest Ethiopia, a recent study found that 47.17% of their 424-person cohort receiving antenatal care reported their pregnancies to be unintended during the COVID-19 pandemic [11]. This study pointed to specific factors such as exposure to community education and lack of healthcare support as factors that increased the likelihood of unintended pregnancy during the COVID-19 pandemic [11]. The incidence of unintended pregnancy in Ethiopia was noted to be 79 per 1,000 women aged 15-49 between 2015 and 2019 [21].

Healthcare Access and Birth Control
Difficulty accessing reproductive health services, the desire to become pregnant, and the use of birth control in those exposed to natural disasters or the COVID-19 pandemic were studied. Difficulty accessing reproductive health services after a natural disaster was noted in one study based on the 2009 Sumatra earthquake in Indonesia, which found that 552/667 (82.8%) respondents reported an increased difficulty in accessing reproductive health services post-earthquake compared to 11/667 (1.6%), who reported no change in accessibility (OR 0.11; 95% CI: 0.08-0.14) [12]. Studies exploring the use of birth control found that there was an increase in the number of women who were not using birth control in the populations exposed to the 2006 Yogyakarta earthquake in Indonesia and Hurricane Katrina in the United States [8,13], while the use of contraception, in general, showed a significant decrease after exposure to the Yogyakarta earthquake [13].
The use of and changes in contraception use were primarily assessed in those exposed to the Sumatra and Yogyakarta earthquakes. A statistically significant decrease in the use of oral contraceptive pills (OCPs) and the number of new IUDs was shown after exposure to the disasters in Sumatra and Yogyakarta, while no relevant change was observed in the continued use of implants, injections, or non-hormonal birth control methods, such as condoms and coitus interruptus [12,13].
During the COVID-19 pandemic, one observational study in Turkey found that of the 58 subjects surveyed, 24 (41.3%) used contraception prior to the pandemic versus only 10 (17.2%) during the pandemic [14]. This value was found to be a statistically significant decrease in the use of contraception (p = 0.004). A statistically significant decrease in the desire to become pregnant as well as an increase in the frequency of sexual intercourse was also found in this cohort [14].
In a survey study in Italy during the COVID-19 pandemic, all 216 married or cohabitating patients continued their method of birth control, both long-acting and short-acting contraceptives, during the pandemic, and none had an unplanned pregnancy [6]. It was also found that 51/101 (50.5%) single women self-discontinued their short-acting reversible contraceptives; however, 47/101 (46.5%) continued with sexual activity despite social distancing rules leading to the 15/101 (14.9%) unintended pregnancies mentioned above [6].

Neonatal Morbidity: A Secondary Outcome
An increase in neonatal morbidity was demonstrated in a cohort study examining the effects of Hurricane Harvey in the United States in 2017 with a rate of 1965/25337 (7.8%) before and 456/3842 (11.9%) after the hurricane (aOR 1.52 [1.34-1.71]) [15]. This is for the composite neonatal morbidity; not all individual components were found to be statistically significant. The authors defined neonatal morbidity as "including any of the following: 5-minute Apgar score ≤ 3, respiratory distress syndrome, the use of ventilator or continuous positive airway pressure, suspected newborn sepsis, seizures, stillbirth, or neonatal death." [15] Components found to be significant were respiratory distress syndrome (aOR 1.  [15]. Short interval pregnancy during the Haitian earthquake was noted as an increase (p < 0.001) (<12 months) post-earthquake from 690/7280 (9.5%) to 1086/7280 (14.9%) [10].

COVID-19 Predicted Outcomes
Two studies utilized predictive algorithms to describe the trajectories of unplanned pregnancy and decreased contraception use due to the COVID-19 pandemic. Additional predictive outcomes included additional maternal deaths, unsafe abortions, and neonatal deaths. The compiled data between the two studies are described in Table 2. A recent study by the United Nations Population Fund (UNFPA) utilized a graded service disruption model to illustrate various outcomes based on the level of disruption (low, medium, and high) and length of disruption (3, 6, 9, and 12 months). It showed that the highest level of a 12-month high service disruption of family planning services could lead to 15,000,000 unplanned pregnancies worldwide [3]. Similarly, a separate study by Riley et al. utilized 2019 sexual and reproductive data from 132 low-to-middle-income countries, up-to-date contraceptive methods/needs, coverage received, and population data to estimate that a 10% decline in family planning services would lead to 15,401,000 unplanned pregnancies worldwide [16]. ,000,000 women unable to use [3] 325,000 [3] 12-month high service disruption 51,000,000 [3] 15,000,000 [3] 10% decline in services 48,558,000 [16] 15,401,000 [16] 28,000 [16] 2,591,000 [16] 168,000 [16] 10% shift in abortion safe to unsafe 1,000 [16] 3,325,000 [16] Average of 12-month disruption and 10% decline 49,779,000 [3,16] 15,200,500 [3,16] [3,16].

Discussion
Infrastructure and supply chain disruptions leave consumers of family planning services at a disadvantage for accessing regular contraceptive methods or emergency contraceptives, therefore leading to an increased risk of unplanned pregnancy [4]. Our review suggests that an increase in unplanned pregnancies was seen during times of natural disaster. It is imperative that as relief efforts and funding are distributed across medical specialties, family planning services should be prioritized and considered as essential services. Furthermore, the overall use of contraceptives, including oral contraceptives and new IUDs, all decreased post-natural disaster pregnancies, further illustrating the need for family planning services to be accessible even during public health emergencies.
While the relationship between the COVID-19 pandemic and unintended pregnancy is still being determined, initial data shows a decreased use of contraceptives, an increase in the frequency of sexual intercourse, and a decrease in the desire to become pregnant [14]. These variables play a vital role in unintended pregnancy and have the potential to increase unintended pregnancy in those exposed to pandemics. Adverse outcomes, such as increases in neonatal morbidity, demonstrate the downstream effects of disruptions in prenatal care and the stressors of childbirth during natural disasters [16].
Some other considerations are the social and policy components within the society which the natural disaster or pandemic is affecting. Factors such as employment, socioeconomic status, social and political determinants of health, and family planning policies affect the outcomes noted in this review, that is, previous public health emergencies and COVID-19 continuing to impact public health [22]. Financial worries and economic instabilities influence a decreased desire for pregnancy while also creating additional barriers to obtaining contraception and family planning services [22].
Social, economic, and racial disparities in health are very apparent during the COVID-19 pandemic [22]. Policy improvements in these sectors are necessary along with those for family planning and contraceptive services. Thus far, in the United States during the COVID-19 pandemic, policy experts have classified family planning services are essential, which has allowed for further care through telemedicine, increased insurance coverage, and increased funding for family planning programs [22].

Limitations
The major limitation of this study is the small number of papers that met the inclusion criteria. Due to this reason, papers that met inclusion criteria were utilized regardless of rating or quality. Only English papers or those with English translations were included in this study further limiting the scope of the study to have a greater focus on European-or American-based studies. Additionally, some of the secondary and adverse outcomes studied in this paper may be due to the effects farther than those described, such as physiologic and complex medical issues of the birthing person prior to earthquake and hurricane exposure. Furthermore, the various natural disasters are occurring at various points in time, which may mean subjects have different desires or relationships with pregnancy and family planning services. Family planning and contraception policies in various countries at these various points in time were not addressed. The predictive COVID-19 data discussed varied based on algorithms or methods utilized leading to potential discrepancies in findings.

Implications
Of the 1.9 billion women of reproductive age worldwide, 1.1 billion require family planning services [23]. Family planning and obstetric providers should be aware of the unique challenges and limitations that accompany natural disasters and pandemics and find ways to facilitate care to prevent unintended pregnancy and adverse effects on the fetus and birthing person.
Currently, the CDC recommends that providers combat the decreased access to family planning services due to the COVID-19 pandemic by utilizing telehealth to see patients in a socially distanced manner [24]. However, providers must also keep the limitations and issues that accompany telehealth in mind. Factors such as access to a stable internet connection and the availability of webcams can make the utilization of telehealth more difficult, especially in socioeconomically disadvantaged communities, potentially creating a greater digital divide [25]. This application of telemedicine for contraceptive and family planning purposes should be prioritized and considered in future pandemics and natural disasters globally, given the increases in unplanned pregnancy rates during these times.
The CDC also recommends that family planning facilities focus on outreach to ensure that patients are aware of their options for acquiring these services [16]. Although CDC recommendations are localized to the United States, similar approaches can be taken worldwide. Other recommendations include utilizing pharmacist-prescribed contraception, prescribing a one-year supply of combined OCPs, and allowing patients to have an "advanced" or an "emergency" supply of OCPs and to utilize self-administered subcutaneous depot medroxyprogesterone acetate (DMPA) [26].

Conclusions
Our review sheds light on the increased risk of unintended pregnancy that accompanies natural disasters and pandemics. This is an important area of research for any future natural disaster or pandemic. While theoretical data shows an increase in the negative outcomes for those seeking family planning services during the COVID-19 pandemic, more research should be done to elucidate the concrete relationship between COVID-19 and unintended pregnancy.

Conflicts of interest:
In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.